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  5. PSME_00049744-RA

PSME_00049744-RA


Description : (p35063|h2ax_picab : 107.0) Histone H2AX - Picea abies (Norway spruce) (Picea excelsa) & (at1g54690 : 102.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 204.0) & (original description: no original description)


Gene families : OG_42_0129880 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00049744-RA
Cluster HCCA clusters: Cluster_411


Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0004664 prephenate dehydratase activity IEP Predicted GO
MF GO:0005085 guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005086 ARF guanyl-nucleotide exchange factor activity IEP Predicted GO
BP GO:0006020 inositol metabolic process IEP Predicted GO
BP GO:0006066 alcohol metabolic process IEP Predicted GO
BP GO:0006558 L-phenylalanine metabolic process IEP Predicted GO
MF GO:0008883 glutamyl-tRNA reductase activity IEP Predicted GO
BP GO:0009094 L-phenylalanine biosynthetic process IEP Predicted GO
BP GO:0009966 regulation of signal transduction IEP Predicted GO
BP GO:0010646 regulation of cell communication IEP Predicted GO
BP GO:0016197 endosomal transport IEP Predicted GO
BP GO:0016482 cytosolic transport IEP Predicted GO
BP GO:0019310 inositol catabolic process IEP Predicted GO
BP GO:0019751 polyol metabolic process IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
BP GO:0023051 regulation of signaling IEP Predicted GO
CC GO:0030906 retromer, cargo-selective complex IEP Predicted GO
BP GO:0032012 regulation of ARF protein signal transduction IEP Predicted GO
BP GO:0033014 tetrapyrrole biosynthetic process IEP Predicted GO
BP GO:0042147 retrograde transport, endosome to Golgi IEP Predicted GO
BP GO:0044275 cellular carbohydrate catabolic process IEP Predicted GO
BP GO:0046164 alcohol catabolic process IEP Predicted GO
BP GO:0046174 polyol catabolic process IEP Predicted GO
BP GO:0046578 regulation of Ras protein signal transduction IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
MF GO:0050113 inositol oxygenase activity IEP Predicted GO
MF GO:0050661 NADP binding IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051056 regulation of small GTPase mediated signal transduction IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
BP GO:1901616 organic hydroxy compound catabolic process IEP Predicted GO
BP GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process IEP Predicted GO
BP GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process IEP Predicted GO
BP GO:1902531 regulation of intracellular signal transduction IEP Predicted GO
InterPro domains Description Start Stop
IPR032454 Histone_H2A_C 104 125
No external refs found!