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Description : (q8w013|comt1_catro : 191.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 178.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 356.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Pseudotsuga release: PSME_00050591-RA | |
| Cluster | HCCA clusters: Cluster_32 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| 96116 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
| At3g53140 | No alias | AT3g53140/T4D2_70 [Source:UniProtKB/TrEMBL;Acc:Q9SCP7] | 0.03 | Orthogroups_2024-Update | |
| Brara.F01513.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
| Brara.H00617.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Brara.I01407.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| GRMZM2G017557 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| GRMZM2G311036 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Glyma.06G137300 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
| Glyma.11G256500 | No alias | O-methyltransferase family protein | 0.04 | Orthogroups_2024-Update | |
| HORVU7Hr1G117890.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Kfl00216_0100 | kfl00216_0100_v1.1 | no hits & (original description: no original description) | 0.02 | Orthogroups_2024-Update | |
| LOC_Os04g09654 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| LOC_Os10g02880 | No alias | O-methyltransferase, putative, expressed | 0.03 | Orthogroups_2024-Update | |
| MA_10426470g0010 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
| MA_10432987g0020 | No alias | (p28002|comt1_medsa : 228.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| MA_86945g0010 | No alias | (at5g54160 : 94.7) A caffeic acid/5-hydroxyferulic acid... | 0.03 | Orthogroups_2024-Update | |
| MA_9153751g0010 | No alias | (q8w013|comt1_catro : 164.0) Caffeic acid... | 0.06 | Orthogroups_2024-Update | |
| MA_9917746g0010 | No alias | (q9fqy8|comt1_capan : 178.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| PSME_00045308-RA | No alias | (p28002|comt1_medsa : 243.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| Seita.1G045400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
| Seita.6G055900.1 | No alias | caffeic acid O-methyltransferase *(COMT) & EC_2.1... | 0.03 | Orthogroups_2024-Update | |
| Seita.6G148100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Seita.7G073700.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Seita.8G210100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.008G061401.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.009G198000.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
| Solyc12g009110 | No alias | O-methyltransferase, putative (AHRD V3.3 *** B9SUX6_RICCO) | 0.02 | Orthogroups_2024-Update | |
| Sopen01g053940 | No alias | O-methyltransferase | 0.03 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0000287 | magnesium ion binding | IEP | Predicted GO |
| MF | GO:0005488 | binding | IEP | Predicted GO |
| MF | GO:0010333 | terpene synthase activity | IEP | Predicted GO |
| MF | GO:0016746 | transferase activity, transferring acyl groups | IEP | Predicted GO |
| MF | GO:0016747 | transferase activity, transferring acyl groups other than amino-acyl groups | IEP | Predicted GO |
| MF | GO:0016829 | lyase activity | IEP | Predicted GO |
| MF | GO:0016835 | carbon-oxygen lyase activity | IEP | Predicted GO |
| MF | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates | IEP | Predicted GO |
| BP | GO:0022618 | ribonucleoprotein complex assembly | IEP | Predicted GO |
| BP | GO:0034622 | cellular protein-containing complex assembly | IEP | Predicted GO |
| BP | GO:0042255 | ribosome assembly | IEP | Predicted GO |
| BP | GO:0042256 | mature ribosome assembly | IEP | Predicted GO |
| MF | GO:0043021 | ribonucleoprotein complex binding | IEP | Predicted GO |
| MF | GO:0043022 | ribosome binding | IEP | Predicted GO |
| MF | GO:0043167 | ion binding | IEP | Predicted GO |
| MF | GO:0043169 | cation binding | IEP | Predicted GO |
| BP | GO:0043933 | protein-containing complex subunit organization | IEP | Predicted GO |
| MF | GO:0044877 | protein-containing complex binding | IEP | Predicted GO |
| MF | GO:0046872 | metal ion binding | IEP | Predicted GO |
| MF | GO:0046983 | protein dimerization activity | IEP | Predicted GO |
| BP | GO:0065003 | protein-containing complex assembly | IEP | Predicted GO |
| BP | GO:0070925 | organelle assembly | IEP | Predicted GO |
| BP | GO:0071826 | ribonucleoprotein complex subunit organization | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR001077 | O_MeTrfase_2 | 1 | 134 |
| No external refs found! |