Description : (p28002|comt1_medsa : 208.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Medicago sativa (Alfalfa) & (at5g54160 : 192.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 372.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00051407-RA | |
Cluster | HCCA clusters: Cluster_180 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
At1g21110 | No alias | Indole glucosinolate O-methyltransferase 3... | 0.05 | Orthogroups_2024-Update | |
Brara.H01339.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.09 | Orthogroups_2024-Update | |
Brara.K00306.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Glyma.09G094400 | No alias | O-methyltransferase family protein | 0.04 | Orthogroups_2024-Update | |
Glyma.14G200800 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.14G200900 | No alias | O-methyltransferase family protein | 0.04 | Orthogroups_2024-Update | |
Glyma.20G213500 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
HORVU1Hr1G001570.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
HORVU7Hr1G117890.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
Kfl00158_0170 | kfl00158_0170_v1.... | (at5g54160 : 162.0) A caffeic acid/5-hydroxyferulic acid... | 0.01 | Orthogroups_2024-Update | |
LOC_Os04g09604 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
MA_10172789g0010 | No alias | (q9fqy8|comt1_capan : 191.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
MA_165197g0010 | No alias | (q8w013|comt1_catro : 372.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
MA_1665780g0010 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
MA_5226589g0010 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
PSME_00016835-RA | No alias | (p28002|comt1_medsa : 153.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00032996-RA | No alias | (q8w013|comt1_catro : 410.0) Caffeic acid... | 0.06 | Orthogroups_2024-Update | |
PSME_00037662-RA | No alias | (q8w013|comt1_catro : 274.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
PSME_00041841-RA | No alias | (q8w013|comt1_catro : 270.0) Caffeic acid... | 0.05 | Orthogroups_2024-Update | |
PSME_00045308-RA | No alias | (p28002|comt1_medsa : 243.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
PSME_00050669-RA | No alias | (q8w013|comt1_catro : 270.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
PSME_00052154-RA | No alias | (q8w013|comt1_catro : 255.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00052715-RA | No alias | (p28002|comt1_medsa : 235.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
Pp1s116_1V6 | No alias | alkaloid o-methyltransferase related | 0.02 | Orthogroups_2024-Update | |
Sobic.001G346800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
Sobic.005G216100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Sobic.005G216200.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Solyc10g008120 | No alias | O-methyltransferase (AHRD V3.3 *** A0A1B4Z3W3_9ROSA) | 0.04 | Orthogroups_2024-Update | |
Sopen10g003990 | No alias | O-methyltransferase | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003885 | D-arabinono-1,4-lactone oxidase activity | IEP | Predicted GO |
BP | GO:0006260 | DNA replication | IEP | Predicted GO |
MF | GO:0015078 | proton transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015298 | solute:cation antiporter activity | IEP | Predicted GO |
MF | GO:0015299 | solute:proton antiporter activity | IEP | Predicted GO |
MF | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor | IEP | Predicted GO |
No external refs found! |