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- Pseudotsuga menziesii
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- PSME_00051796-RA
PSME_00051796-RA
Description : (at2g30110 : 480.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (p31251|ube12_wheat : 470.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (reliability: 960.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00051796-RA | |
Cluster | HCCA clusters: Cluster_87 | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0003824 | catalytic activity | None | Extended |
MF | GO:0008641 | ubiquitin-like modifier activating enzyme activity | IEA | InterProScan predictions |
MF | GO:0016874 | ligase activity | None | Extended |
MF | GO:0016877 | ligase activity, forming carbon-sulfur bonds | None | Extended |
Type | GO Term | Name | Evidence | Source |
MF | GO:0005215 | transporter activity | IEP | Predicted GO |
CC | GO:0005575 | cellular_component | IEP | Predicted GO |
BP | GO:0006810 | transport | IEP | Predicted GO |
MF | GO:0010181 | FMN binding | IEP | Predicted GO |
MF | GO:0015399 | primary active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | IEP | Predicted GO |
CC | GO:0016021 | integral component of membrane | IEP | Predicted GO |
MF | GO:0022857 | transmembrane transporter activity | IEP | Predicted GO |
CC | GO:0031224 | intrinsic component of membrane | IEP | Predicted GO |
MF | GO:0042623 | ATPase activity, coupled | IEP | Predicted GO |
MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEP | Predicted GO |
MF | GO:0043492 | ATPase activity, coupled to movement of substances | IEP | Predicted GO |
CC | GO:0044425 | membrane part | IEP | Predicted GO |
MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
MF | GO:0050662 | coenzyme binding | IEP | Predicted GO |
BP | GO:0051179 | localization | IEP | Predicted GO |
BP | GO:0051234 | establishment of localization | IEP | Predicted GO |
BP | GO:0055085 | transmembrane transport | IEP | Predicted GO |