Description : (q8w013|comt1_catro : 208.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 204.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 388.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00052449-RA | |
Cluster | HCCA clusters: Cluster_136 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
PSME_00015141-RA | No alias | (q8w013|comt1_catro : 194.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00016370-RA | No alias | (q8w013|comt1_catro : 219.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00023722-RA | No alias | (p28002|comt1_medsa : 233.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00041945-RA | No alias | (q8w013|comt1_catro : 154.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00041946-RA | No alias | (o82054|comt1_sacof : 182.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
PSME_00047714-RA | No alias | (q06509|comt1_maize : 221.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00051686-RA | No alias | (p28002|comt1_medsa : 274.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
PSME_00052626-RA | No alias | (p28002|comt1_medsa : 204.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003899 | DNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
BP | GO:0006351 | transcription, DNA-templated | IEP | Predicted GO |
MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
BP | GO:0032774 | RNA biosynthetic process | IEP | Predicted GO |
MF | GO:0033926 | glycopeptide alpha-N-acetylgalactosaminidase activity | IEP | Predicted GO |
MF | GO:0034062 | 5'-3' RNA polymerase activity | IEP | Predicted GO |
BP | GO:0097659 | nucleic acid-templated transcription | IEP | Predicted GO |
MF | GO:0097747 | RNA polymerase activity | IEP | Predicted GO |
MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
MF | GO:0140103 | catalytic activity, acting on a glycoprotein | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001077 | O_MeTrfase_2 | 61 | 287 |
No external refs found! |