PSME_00052764-RA


Description : (p35063|h2ax_picab : 225.0) Histone H2AX - Picea abies (Norway spruce) (Picea excelsa) & (at1g54690 : 202.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 404.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00052764-RA
Cluster HCCA clusters: Cluster_70

Target Alias Description ECC score Gene Family Method Actions
At1g08880 No alias Histone H2A [Source:UniProtKB/TrEMBL;Acc:A0A178W8H7] 0.02 Orthogroups_2024-Update
At1g51060 No alias Probable histone H2A.1 [Source:UniProtKB/Swiss-Prot;Acc:Q9C681] 0.02 Orthogroups_2024-Update
Bradi2g23090 No alias histone H2A 12 0.04 Orthogroups_2024-Update
Brara.B03550.1 No alias histone *(H2A) 0.02 Orthogroups_2024-Update
Brara.E02150.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
LOC_Os03g17100 No alias Core histone H2A/H2B/H3/H4 domain containing protein,... 0.02 Orthogroups_2024-Update
MA_924620g0010 No alias (q2hu68|h2a1_medtr : 180.0) Probable histone H2A.1 -... 0.03 Orthogroups_2024-Update
PSME_00017670-RA No alias (p35063|h2ax_picab : 188.0) Histone H2AX - Picea abies... 0.05 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
BP GO:0030490 maturation of SSU-rRNA IEP Predicted GO
MF GO:0030515 snoRNA binding IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
InterPro domains Description Start Stop
IPR032454 Histone_H2A_C 95 128
IPR007125 Histone_H2A/H2B/H3 7 92
No external refs found!