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  5. PSME_00052950-RA

PSME_00052950-RA


Description : "(at2g47460 : 140.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p20026|myb1_horvu : 136.0) Myb-related protein Hv1 - Hordeum vulgare (Barley) & (reliability: 280.0) & (original description: no original description)"


Gene families : OG_42_0130399 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00052950-RA
Cluster HCCA clusters: Cluster_708


Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
BP GO:0044265 cellular macromolecule catabolic process IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001005 SANT/Myb 24 53
IPR001005 SANT/Myb 62 101
No external refs found!