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Description : (p28002|comt1_medsa : 233.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Medicago sativa (Alfalfa) & (at5g54160 : 219.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 432.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Pseudotsuga release: PSME_00053053-RA | |
| Cluster | HCCA clusters: Cluster_249 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| 412283 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| GRMZM2G140996 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| HORVU3Hr1G110170.3 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| HORVU6Hr1G000040.1 | No alias | caffeic acid O-methyltransferase *(COMT) & EC_2.1... | 0.02 | Orthogroups_2024-Update | |
| LOC_Os04g09604 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| LOC_Os06g16960 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| LOC_Os08g19420 | No alias | O-methyltransferase, putative, expressed | 0.03 | Orthogroups_2024-Update | |
| LOC_Os11g20080 | No alias | O-methyltransferase, putative, expressed | 0.03 | Orthogroups_2024-Update | |
| LOC_Os12g10170 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| LOC_Os12g25860 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| MA_10432987g0020 | No alias | (p28002|comt1_medsa : 228.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
| MA_5226589g0010 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
| MA_74925g0020 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
| MA_86945g0010 | No alias | (at5g54160 : 94.7) A caffeic acid/5-hydroxyferulic acid... | 0.03 | Orthogroups_2024-Update | |
| Mp4g03520.1 | No alias | (S)-scoulerine 9-O-methyltransferase OS=Coptis japonica... | 0.02 | Orthogroups_2024-Update | |
| PSME_00002255-RA | No alias | (q9fqy8|comt1_capan : 423.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| PSME_00009782-RA | No alias | (q9fqy8|comt1_capan : 433.0) Caffeic acid... | 0.05 | Orthogroups_2024-Update | |
| PSME_00018604-RA | No alias | (o82054|comt1_sacof : 167.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| PSME_00047714-RA | No alias | (q06509|comt1_maize : 221.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
| Seita.6G055900.1 | No alias | caffeic acid O-methyltransferase *(COMT) & EC_2.1... | 0.04 | Orthogroups_2024-Update | |
| Seita.6G174800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Seita.9G374200.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.004G341500.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
| Sobic.007G058800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.05 | Orthogroups_2024-Update | |
| Sobic.007G059100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Sobic.009G197800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.010G234400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Solyc10g008120 | No alias | O-methyltransferase (AHRD V3.3 *** A0A1B4Z3W3_9ROSA) | 0.03 | Orthogroups_2024-Update | |
| Solyc12g041960 | No alias | O-methyltransferase (AHRD V3.3 *** A0A1B4Z3W3_9ROSA) | 0.02 | Orthogroups_2024-Update | |
| Sopen01g053940 | No alias | O-methyltransferase | 0.02 | Orthogroups_2024-Update | |
| Sopen03g028450 | No alias | O-methyltransferase | 0.03 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
| MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0003885 | D-arabinono-1,4-lactone oxidase activity | IEP | Predicted GO |
| MF | GO:0004175 | endopeptidase activity | IEP | Predicted GO |
| MF | GO:0004252 | serine-type endopeptidase activity | IEP | Predicted GO |
| MF | GO:0004555 | alpha,alpha-trehalase activity | IEP | Predicted GO |
| MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
| BP | GO:0005991 | trehalose metabolic process | IEP | Predicted GO |
| BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
| BP | GO:0008150 | biological_process | IEP | Predicted GO |
| BP | GO:0008152 | metabolic process | IEP | Predicted GO |
| MF | GO:0015927 | trehalase activity | IEP | Predicted GO |
| MF | GO:0016491 | oxidoreductase activity | IEP | Predicted GO |
| MF | GO:0016840 | carbon-nitrogen lyase activity | IEP | Predicted GO |
| MF | GO:0016843 | amine-lyase activity | IEP | Predicted GO |
| MF | GO:0016844 | strictosidine synthase activity | IEP | Predicted GO |
| MF | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor | IEP | Predicted GO |
| MF | GO:0020037 | heme binding | IEP | Predicted GO |
| MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
| MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
| BP | GO:0055114 | oxidation-reduction process | IEP | Predicted GO |
| MF | GO:0140096 | catalytic activity, acting on a protein | IEP | Predicted GO |
| No external refs found! |