Description : (at2g36910 : 170.0) Belongs to the family of ATP-binding cassette (ABC) transporters. Also known as AtMDR1.Possibly regulates auxin-dependent responses by influencing basipetal auxin transport in the root. Exerts nonredundant, partially overlapping functions with the ABC transporter encoded by AT3G28860. PGP1 mediates cellular efflux of IAA and interacts with PIN genes that may confer an accelerated vectoral component to PGP-mediated transport. The non-polar localization of PGP1 at root and shoot apices, where IAA gradient-driven transport is impaired, may be required to confer directionality to auxin transport in those tissues.; ATP binding cassette subfamily B1 (ABCB1); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, calmodulin binding, auxin efflux transmembrane transporter activity; INVOLVED IN: in 10 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ATP binding cassette subfamily B19 (TAIR:AT3G28860.1); Has 825599 Blast hits to 386427 proteins in 4134 species: Archae - 14573; Bacteria - 644325; Metazoa - 17752; Fungi - 12077; Plants - 9020; Viruses - 35; Other Eukaryotes - 127817 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 85.9) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 340.0) & (original description: no original description)
Gene families : OG_42_0130439 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00053181-RA | |
Cluster | HCCA clusters: Cluster_137 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | InterProScan predictions |
BP | GO:0055085 | transmembrane transport | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
BP | GO:0005984 | disaccharide metabolic process | IEP | Predicted GO |
BP | GO:0005985 | sucrose metabolic process | IEP | Predicted GO |
BP | GO:0006464 | cellular protein modification process | IEP | Predicted GO |
BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0009311 | oligosaccharide metabolic process | IEP | Predicted GO |
CC | GO:0009521 | photosystem | IEP | Predicted GO |
CC | GO:0009523 | photosystem II | IEP | Predicted GO |
BP | GO:0009987 | cellular process | IEP | Predicted GO |
BP | GO:0015979 | photosynthesis | IEP | Predicted GO |
MF | GO:0016157 | sucrose synthase activity | IEP | Predicted GO |
MF | GO:0016301 | kinase activity | IEP | Predicted GO |
BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEP | Predicted GO |
MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
MF | GO:0030145 | manganese ion binding | IEP | Predicted GO |
BP | GO:0036211 | protein modification process | IEP | Predicted GO |
BP | GO:0043412 | macromolecule modification | IEP | Predicted GO |
BP | GO:0044237 | cellular metabolic process | IEP | Predicted GO |
CC | GO:0044436 | thylakoid part | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR011527 | ABC1_TM_dom | 42 | 129 |
No external refs found! |