Description : (at5g57090 : 241.0) Encodes an auxin efflux carrier that is similar to bacterial membrane transporters. Root-specific role in the transport of auxin. Acts downstream of CTR1 and ethylene biosynthesis, in the same pathway as EIN2 and AUX1, and independent from EIN3 and EIN5/AIN1 pathway. In the root, the protein localizes apically in epidermal and lateral root cap cells and predominantly basally in cortical cells. Functions may be regulated by phosphorylation status. EIR1 expression is induced by brassinolide treatment in the brassinosteroid-insensitive br1 mutant. Gravistimulation resulted in asymmetric PIN2 distribution, with more protein degraded at the upper side of the gravistimulated root. Protein turnover is affected by the proteasome and by endosomal cycling. Plasma membrane-localized PIN proteins mediate a saturable efflux of auxin. PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. The action of PINs in auxin efflux is distinct from PGPs, rate-limiting, specific to auxins and sensitive to auxin transport inhibitors. Membrane sterol composition is essential for the acquisition of PIN2 polarity.; ETHYLENE INSENSITIVE ROOT 1 (EIR1); CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT2G01420.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q5smq9|pin1_orysa : 195.0) Auxin efflux carrier component 1 (OsPIN1) (Ethylene insensitive root 1 homolog) - Oryza sativa (Rice) & (reliability: 482.0) & (original description: no original description)
Gene families : OG_42_0000235 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000235_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00053453-RA | |
Cluster | HCCA clusters: Cluster_307 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Mp3g21660.1 | No alias | auxin transporter (PIN). auxin efflux transporter (PIN) | 0.02 | Orthogroups_2024-Update | |
PSME_00040058-RA | No alias | (at5g57090 : 363.0) Encodes an auxin efflux carrier that... | 0.04 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
BP | GO:0055085 | transmembrane transport | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
CC | GO:0005576 | extracellular region | IEP | Predicted GO |
CC | GO:0005618 | cell wall | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0005976 | polysaccharide metabolic process | IEP | Predicted GO |
BP | GO:0006606 | protein import into nucleus | IEP | Predicted GO |
BP | GO:0006886 | intracellular protein transport | IEP | Predicted GO |
BP | GO:0006913 | nucleocytoplasmic transport | IEP | Predicted GO |
BP | GO:0008104 | protein localization | IEP | Predicted GO |
BP | GO:0015031 | protein transport | IEP | Predicted GO |
BP | GO:0015833 | peptide transport | IEP | Predicted GO |
MF | GO:0016762 | xyloglucan:xyloglucosyl transferase activity | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
MF | GO:0016829 | lyase activity | IEP | Predicted GO |
MF | GO:0016846 | carbon-sulfur lyase activity | IEP | Predicted GO |
BP | GO:0017038 | protein import | IEP | Predicted GO |
CC | GO:0030312 | external encapsulating structure | IEP | Predicted GO |
BP | GO:0033036 | macromolecule localization | IEP | Predicted GO |
BP | GO:0033365 | protein localization to organelle | IEP | Predicted GO |
BP | GO:0034504 | protein localization to nucleus | IEP | Predicted GO |
BP | GO:0034613 | cellular protein localization | IEP | Predicted GO |
BP | GO:0042886 | amide transport | IEP | Predicted GO |
BP | GO:0045184 | establishment of protein localization | IEP | Predicted GO |
BP | GO:0046907 | intracellular transport | IEP | Predicted GO |
CC | GO:0048046 | apoplast | IEP | Predicted GO |
BP | GO:0051169 | nuclear transport | IEP | Predicted GO |
BP | GO:0051170 | import into nucleus | IEP | Predicted GO |
BP | GO:0051641 | cellular localization | IEP | Predicted GO |
BP | GO:0051649 | establishment of localization in cell | IEP | Predicted GO |
MF | GO:0061608 | nuclear import signal receptor activity | IEP | Predicted GO |
BP | GO:0070727 | cellular macromolecule localization | IEP | Predicted GO |
BP | GO:0072594 | establishment of protein localization to organelle | IEP | Predicted GO |
MF | GO:0140104 | molecular carrier activity | IEP | Predicted GO |
MF | GO:0140142 | nucleocytoplasmic carrier activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR004776 | Mem_trans | 3 | 185 |
No external refs found! |