PSME_00053453-RA


Description : (at5g57090 : 241.0) Encodes an auxin efflux carrier that is similar to bacterial membrane transporters. Root-specific role in the transport of auxin. Acts downstream of CTR1 and ethylene biosynthesis, in the same pathway as EIN2 and AUX1, and independent from EIN3 and EIN5/AIN1 pathway. In the root, the protein localizes apically in epidermal and lateral root cap cells and predominantly basally in cortical cells. Functions may be regulated by phosphorylation status. EIR1 expression is induced by brassinolide treatment in the brassinosteroid-insensitive br1 mutant. Gravistimulation resulted in asymmetric PIN2 distribution, with more protein degraded at the upper side of the gravistimulated root. Protein turnover is affected by the proteasome and by endosomal cycling. Plasma membrane-localized PIN proteins mediate a saturable efflux of auxin. PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. The action of PINs in auxin efflux is distinct from PGPs, rate-limiting, specific to auxins and sensitive to auxin transport inhibitors. Membrane sterol composition is essential for the acquisition of PIN2 polarity.; ETHYLENE INSENSITIVE ROOT 1 (EIR1); CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT2G01420.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q5smq9|pin1_orysa : 195.0) Auxin efflux carrier component 1 (OsPIN1) (Ethylene insensitive root 1 homolog) - Oryza sativa (Rice) & (reliability: 482.0) & (original description: no original description)


Gene families : OG_42_0000235 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000235_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00053453-RA
Cluster HCCA clusters: Cluster_307

Target Alias Description ECC score Gene Family Method Actions
Mp3g21660.1 No alias auxin transporter (PIN). auxin efflux transporter (PIN) 0.02 Orthogroups_2024-Update
PSME_00040058-RA No alias (at5g57090 : 363.0) Encodes an auxin efflux carrier that... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0016021 integral component of membrane IEA InterProScan predictions
BP GO:0055085 transmembrane transport IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
CC GO:0005576 extracellular region IEP Predicted GO
CC GO:0005618 cell wall IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0005976 polysaccharide metabolic process IEP Predicted GO
BP GO:0006606 protein import into nucleus IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
MF GO:0016762 xyloglucan:xyloglucosyl transferase activity IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016846 carbon-sulfur lyase activity IEP Predicted GO
BP GO:0017038 protein import IEP Predicted GO
CC GO:0030312 external encapsulating structure IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0033365 protein localization to organelle IEP Predicted GO
BP GO:0034504 protein localization to nucleus IEP Predicted GO
BP GO:0034613 cellular protein localization IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
CC GO:0048046 apoplast IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051170 import into nucleus IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
MF GO:0061608 nuclear import signal receptor activity IEP Predicted GO
BP GO:0070727 cellular macromolecule localization IEP Predicted GO
BP GO:0072594 establishment of protein localization to organelle IEP Predicted GO
MF GO:0140104 molecular carrier activity IEP Predicted GO
MF GO:0140142 nucleocytoplasmic carrier activity IEP Predicted GO
InterPro domains Description Start Stop
IPR004776 Mem_trans 3 185
No external refs found!