Description : (at1g75950 : 185.0) SKP1 is core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Predominately expressed from leptotene to pachytene. Negatively regulates recombination. Interacts with P0, a silencing suppressor protein encoded by poleroviruses by means of a conserved minimal F-box motif.; S phase kinase-associated protein 1 (SKP1); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: negative regulation of DNA recombination, response to cadmium ion, mitosis, male meiosis, ubiquitin-dependent protein catabolic process; LOCATED IN: in 7 components; EXPRESSED IN: 35 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein (TAIR:AT5G42190.1); Has 1455 Blast hits to 1451 proteins in 268 species: Archae - 0; Bacteria - 0; Metazoa - 552; Fungi - 179; Plants - 538; Viruses - 11; Other Eukaryotes - 175 (source: NCBI BLink). & (reliability: 370.0) & (original description: no original description)
Gene families : OG_42_0000356 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000356_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00055606-RA | |
Cluster | HCCA clusters: Cluster_67 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
PSME_00013848-RA | No alias | (at5g42190 : 187.0) Similar to SKP1 in yeast and humans... | 0.04 | Orthogroups_2024-Update | |
Sobic.003G197600.2 | No alias | ASK-type linker component of SCF E3 ubiquitin ligase complexes | 0.04 | Orthogroups_2024-Update | |
Sobic.010G218900.2 | No alias | ASK-type linker component of SCF E3 ubiquitin ligase complexes | 0.02 | Orthogroups_2024-Update | |
Solyc10g055610 | No alias | SKP1-like protein (AHRD V3.3 *** O82463_NICCL) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006511 | ubiquitin-dependent protein catabolic process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000271 | polysaccharide biosynthetic process | IEP | Predicted GO |
MF | GO:0003777 | microtubule motor activity | IEP | Predicted GO |
MF | GO:0004523 | RNA-DNA hybrid ribonuclease activity | IEP | Predicted GO |
MF | GO:0004888 | transmembrane signaling receptor activity | IEP | Predicted GO |
MF | GO:0004970 | ionotropic glutamate receptor activity | IEP | Predicted GO |
MF | GO:0005215 | transporter activity | IEP | Predicted GO |
MF | GO:0005216 | ion channel activity | IEP | Predicted GO |
MF | GO:0005230 | extracellular ligand-gated ion channel activity | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0006367 | transcription initiation from RNA polymerase II promoter | IEP | Predicted GO |
BP | GO:0006928 | movement of cell or subcellular component | IEP | Predicted GO |
BP | GO:0007017 | microtubule-based process | IEP | Predicted GO |
BP | GO:0007018 | microtubule-based movement | IEP | Predicted GO |
MF | GO:0008017 | microtubule binding | IEP | Predicted GO |
MF | GO:0008066 | glutamate receptor activity | IEP | Predicted GO |
MF | GO:0008092 | cytoskeletal protein binding | IEP | Predicted GO |
BP | GO:0009250 | glucan biosynthetic process | IEP | Predicted GO |
MF | GO:0015075 | ion transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015267 | channel activity | IEP | Predicted GO |
MF | GO:0015276 | ligand-gated ion channel activity | IEP | Predicted GO |
MF | GO:0015318 | inorganic molecular entity transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015631 | tubulin binding | IEP | Predicted GO |
CC | GO:0016020 | membrane | IEP | Predicted GO |
MF | GO:0016787 | hydrolase activity | IEP | Predicted GO |
MF | GO:0022803 | passive transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0022824 | transmitter-gated ion channel activity | IEP | Predicted GO |
MF | GO:0022834 | ligand-gated channel activity | IEP | Predicted GO |
MF | GO:0022835 | transmitter-gated channel activity | IEP | Predicted GO |
MF | GO:0022836 | gated channel activity | IEP | Predicted GO |
MF | GO:0022838 | substrate-specific channel activity | IEP | Predicted GO |
MF | GO:0022839 | ion gated channel activity | IEP | Predicted GO |
MF | GO:0022857 | transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0030594 | neurotransmitter receptor activity | IEP | Predicted GO |
BP | GO:0033692 | cellular polysaccharide biosynthetic process | IEP | Predicted GO |
BP | GO:0034637 | cellular carbohydrate biosynthetic process | IEP | Predicted GO |
MF | GO:0038023 | signaling receptor activity | IEP | Predicted GO |
BP | GO:0051273 | beta-glucan metabolic process | IEP | Predicted GO |
BP | GO:0051274 | beta-glucan biosynthetic process | IEP | Predicted GO |
MF | GO:0060089 | molecular transducer activity | IEP | Predicted GO |
No external refs found! |