PSME_00055606-RA


Description : (at1g75950 : 185.0) SKP1 is core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Predominately expressed from leptotene to pachytene. Negatively regulates recombination. Interacts with P0, a silencing suppressor protein encoded by poleroviruses by means of a conserved minimal F-box motif.; S phase kinase-associated protein 1 (SKP1); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: negative regulation of DNA recombination, response to cadmium ion, mitosis, male meiosis, ubiquitin-dependent protein catabolic process; LOCATED IN: in 7 components; EXPRESSED IN: 35 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein (TAIR:AT5G42190.1); Has 1455 Blast hits to 1451 proteins in 268 species: Archae - 0; Bacteria - 0; Metazoa - 552; Fungi - 179; Plants - 538; Viruses - 11; Other Eukaryotes - 175 (source: NCBI BLink). & (reliability: 370.0) & (original description: no original description)


Gene families : OG_42_0000356 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000356_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00055606-RA
Cluster HCCA clusters: Cluster_67

Target Alias Description ECC score Gene Family Method Actions
PSME_00013848-RA No alias (at5g42190 : 187.0) Similar to SKP1 in yeast and humans... 0.04 Orthogroups_2024-Update
Sobic.003G197600.2 No alias ASK-type linker component of SCF E3 ubiquitin ligase complexes 0.04 Orthogroups_2024-Update
Sobic.010G218900.2 No alias ASK-type linker component of SCF E3 ubiquitin ligase complexes 0.02 Orthogroups_2024-Update
Solyc10g055610 No alias SKP1-like protein (AHRD V3.3 *** O82463_NICCL) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006511 ubiquitin-dependent protein catabolic process IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000271 polysaccharide biosynthetic process IEP Predicted GO
MF GO:0003777 microtubule motor activity IEP Predicted GO
MF GO:0004523 RNA-DNA hybrid ribonuclease activity IEP Predicted GO
MF GO:0004888 transmembrane signaling receptor activity IEP Predicted GO
MF GO:0004970 ionotropic glutamate receptor activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005230 extracellular ligand-gated ion channel activity IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006367 transcription initiation from RNA polymerase II promoter IEP Predicted GO
BP GO:0006928 movement of cell or subcellular component IEP Predicted GO
BP GO:0007017 microtubule-based process IEP Predicted GO
BP GO:0007018 microtubule-based movement IEP Predicted GO
MF GO:0008017 microtubule binding IEP Predicted GO
MF GO:0008066 glutamate receptor activity IEP Predicted GO
MF GO:0008092 cytoskeletal protein binding IEP Predicted GO
BP GO:0009250 glucan biosynthetic process IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0015276 ligand-gated ion channel activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
MF GO:0015631 tubulin binding IEP Predicted GO
CC GO:0016020 membrane IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
MF GO:0022824 transmitter-gated ion channel activity IEP Predicted GO
MF GO:0022834 ligand-gated channel activity IEP Predicted GO
MF GO:0022835 transmitter-gated channel activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0030594 neurotransmitter receptor activity IEP Predicted GO
BP GO:0033692 cellular polysaccharide biosynthetic process IEP Predicted GO
BP GO:0034637 cellular carbohydrate biosynthetic process IEP Predicted GO
MF GO:0038023 signaling receptor activity IEP Predicted GO
BP GO:0051273 beta-glucan metabolic process IEP Predicted GO
BP GO:0051274 beta-glucan biosynthetic process IEP Predicted GO
MF GO:0060089 molecular transducer activity IEP Predicted GO
InterPro domains Description Start Stop
IPR016072 Skp1_comp_dimer 109 155
IPR016073 Skp1_comp_POZ 6 63
No external refs found!