Bradi3g05160

Description : hydroxymethylbilane synthase

Gene families : OG_42_0004692 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004692_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Brachypodium release: Bradi3g05160
Cluster	HCCA clusters: Cluster_71

Target	Alias	Description	ECC score	Gene Family Method
164683	No alias	hydroxymethylbilane synthase	0.04	Orthogroups_2024-Update
Brara.B00276.1	No alias	porphobilinogen deaminase *(HEMC) & EC_2.5 transferase...	0.06	Orthogroups_2024-Update
Brara.C00339.1	No alias	porphobilinogen deaminase *(HEMC) & EC_2.5 transferase...	0.05	Orthogroups_2024-Update
Brara.J02437.1	No alias	porphobilinogen deaminase *(HEMC) & EC_2.5 transferase...	0.05	Orthogroups_2024-Update
Cre16.g663900	No alias	hydroxymethylbilane synthase	0.07	Orthogroups_2024-Update
GRMZM2G026117	No alias	hydroxymethylbilane synthase	0.04	Orthogroups_2024-Update
GRMZM2G041159	No alias	hydroxymethylbilane synthase	0.04	Orthogroups_2024-Update
Glyma.01G227400	No alias	hydroxymethylbilane synthase	0.05	Orthogroups_2024-Update
HORVU6Hr1G028050.1	No alias	porphobilinogen deaminase *(HEMC) & EC_2.5 transferase...	0.03	Orthogroups_2024-Update
LOC_Os02g07230	No alias	porphobilinogen deaminase, chloroplast precursor,...	0.03	Orthogroups_2024-Update
Pp1s116_53V6	No alias	porphobilinogen deaminase	0.03	Orthogroups_2024-Update
Pp1s307_65V6	No alias	porphobilinogen deaminase	0.02	Orthogroups_2024-Update
Seita.1G073800.1	No alias	porphobilinogen deaminase *(HEMC) & EC_2.5 transferase...	0.11	Orthogroups_2024-Update
Solyc07g066470	No alias	Porphobilinogen deaminase, putative (AHRD V3.3 *** B9S2Z0_RICCO)	0.02	Orthogroups_2024-Update
evm.model.tig00000241.50	No alias	(q43082\|hem3_pea : 177.0) Porphobilinogen deaminase,...	0.06	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004418	hydroxymethylbilane synthase activity	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	IEA	InterProScan predictions
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEP	Predicted GO
BP	GO:0001522	pseudouridine synthesis	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003747	translation release factor activity	IEP	Predicted GO
MF	GO:0004109	coproporphyrinogen oxidase activity	IEP	Predicted GO
MF	GO:0004655	porphobilinogen synthase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004827	proline-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004832	valine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005741	mitochondrial outer membrane	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006415	translational termination	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006433	prolyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006553	lysine metabolic process	IEP	Predicted GO
BP	GO:0006605	protein targeting	IEP	Predicted GO
BP	GO:0006612	protein targeting to membrane	IEP	Predicted GO
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
MF	GO:0008079	translation termination factor activity	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008312	7S RNA binding	IEP	Predicted GO
MF	GO:0008565	protein transporter activity	IEP	Predicted GO
MF	GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009085	lysine biosynthetic process	IEP	Predicted GO
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
MF	GO:0009982	pseudouridine synthase activity	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Predicted GO
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016829	lyase activity	IEP	Predicted GO
MF	GO:0016830	carbon-carbon lyase activity	IEP	Predicted GO
MF	GO:0016831	carboxy-lyase activity	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016866	intramolecular transferase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
MF	GO:0019843	rRNA binding	IEP	Predicted GO
BP	GO:0022411	cellular component disassembly	IEP	Predicted GO
BP	GO:0030258	lipid modification	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0031968	organelle outer membrane	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0032977	membrane insertase activity	IEP	Predicted GO
BP	GO:0032984	protein-containing complex disassembly	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
BP	GO:0033365	protein localization to organelle	IEP	Predicted GO
BP	GO:0034613	cellular protein localization	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0042802	identical protein binding	IEP	Predicted GO
MF	GO:0042803	protein homodimerization activity	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0043624	cellular protein complex disassembly	IEP	Predicted GO
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0045047	protein targeting to ER	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0046451	diaminopimelate metabolic process	IEP	Predicted GO
BP	GO:0046834	lipid phosphorylation	IEP	Predicted GO
BP	GO:0046854	phosphatidylinositol phosphorylation	IEP	Predicted GO
CC	GO:0048500	signal recognition particle	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051188	cofactor biosynthetic process	IEP	Predicted GO
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
BP	GO:0070727	cellular macromolecule localization	IEP	Predicted GO
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
MF	GO:0071949	FAD binding	IEP	Predicted GO
BP	GO:0072594	establishment of protein localization to organelle	IEP	Predicted GO
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0072657	protein localization to membrane	IEP	Predicted GO
BP	GO:0090150	establishment of protein localization to membrane	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
CC	GO:0098805	whole membrane	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR022418	Porphobilinogen_deaminase_C	273	345
IPR022417	Porphobilin_deaminase_N	49	260

External Links

No external refs found!

Bradi3g05160

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation