GRMZM2G136465

Description : hydroxy methylglutaryl CoA reductase 1

Gene families : OG_42_0001334 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001334_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Zea release: GRMZM2G136465
Cluster	HCCA clusters: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method
Glyma.20G058000	No alias	hydroxy methylglutaryl CoA reductase 1	0.03	Orthogroups_2024-Update
HORVU6Hr1G070060.4	No alias	3-hydroxy-3-methylglutaryl-CoA reductase & EC_1.1...	0.02	Orthogroups_2024-Update
HORVU7Hr1G051260.3	No alias	3-hydroxy-3-methylglutaryl-CoA reductase & EC_1.1...	0.03	Orthogroups_2024-Update
Potri.005G257000	No alias	hydroxy methylglutaryl CoA reductase 1	0.05	Orthogroups_2024-Update
Potri.011G145000	No alias	hydroxy methylglutaryl CoA reductase 1	0.03	Orthogroups_2024-Update
Pp1s139_2V6	No alias	3-hydroxy-3-methylglutaryl coenzyme a reductase	0.02	Orthogroups_2024-Update
Solyc02g082260	No alias	3-hydroxy-3-methylglutaryl CoA reductase	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006732	coenzyme metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015936	coenzyme A metabolic process	IEA	InterProScan predictions
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0033865	nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	IEA	InterProScan predictions
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	IEP	Predicted GO
MF	GO:0004177	aminopeptidase activity	IEP	Predicted GO
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	Predicted GO
BP	GO:0006694	steroid biosynthetic process	IEP	Predicted GO
BP	GO:0007049	cell cycle	IEP	Predicted GO
BP	GO:0008202	steroid metabolic process	IEP	Predicted GO
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
MF	GO:0008716	D-alanine-D-alanine ligase activity	IEP	Predicted GO
MF	GO:0016229	steroid dehydrogenase activity	IEP	Predicted GO
BP	GO:0016458	gene silencing	IEP	Predicted GO
BP	GO:0016567	protein ubiquitination	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0016881	acid-amino acid ligase activity	IEP	Predicted GO
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	Predicted GO
BP	GO:0031047	gene silencing by RNA	IEP	Predicted GO
BP	GO:0032446	protein modification by small protein conjugation	IEP	Predicted GO
MF	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
BP	GO:0051321	meiotic cell cycle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002202	HMG_CoA_Rdtase	151	362
IPR002202	HMG_CoA_Rdtase	391	577

External Links

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GRMZM2G136465

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation