At2g16440

Description : DNA replication licensing factor MCM4 [Source:UniProtKB/Swiss-Prot;Acc:Q0WVF5]

Gene families : OG_42_0007572 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007572_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Arabidopsis release: At2g16440
Cluster	HCCA clusters: Cluster_6

Target	Alias	Description	ECC score	Gene Family Method
Bradi2g40600	No alias	Minichromosome maintenance (MCM2/3/5) family protein	0.07	Orthogroups_2024-Update
Brara.C04147.1	No alias	component *(MCM4) of MCM replicative DNA helicase complex	0.11	Orthogroups_2024-Update
Cre07.g316850	No alias	Minichromosome maintenance (MCM2/3/5) family protein	0.06	Orthogroups_2024-Update
Glyma.11G113300	No alias	Minichromosome maintenance (MCM2/3/5) family protein	0.07	Orthogroups_2024-Update
Glyma.12G039200	No alias	Minichromosome maintenance (MCM2/3/5) family protein	0.07	Orthogroups_2024-Update
Kfl00033_0310	kfl00033_0310_v1.1	(at2g16440 : 825.0) MINICHROMOSOME MAINTENANCE 4 (MCM4);...	0.05	Orthogroups_2024-Update
Mp3g02380.1	No alias	component MCM4 of MCM replicative DNA helicase complex	0.03	Orthogroups_2024-Update
Potri.009G121500	No alias	Minichromosome maintenance (MCM2/3/5) family protein	0.03	Orthogroups_2024-Update
Seita.5G192100.1	No alias	component *(MCM4) of MCM replicative DNA helicase complex	0.09	Orthogroups_2024-Update
Sobic.003G183700.1	No alias	component *(MCM4) of MCM replicative DNA helicase complex	0.07	Orthogroups_2024-Update
Solyc01g110130	No alias	DNA helicase (AHRD V3.3 *** K4B3M6_SOLLC)	0.07	Orthogroups_2024-Update
Sopen01g052290	No alias	MCM2/3/5 family	0.03	Orthogroups_2024-Update
evm.model.contig_493.10	No alias	(at2g16440 : 599.0) MINICHROMOSOME MAINTENANCE 4 (MCM4);...	0.06	Orthogroups_2024-Update
evm.model.tig00000144.164	No alias	(at2g16440 : 634.0) MINICHROMOSOME MAINTENANCE 4 (MCM4);...	0.06	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006270	DNA replication initiation	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Predicted GO
BP	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003896	DNA primase activity	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006310	DNA recombination	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
MF	GO:0008097	5S rRNA binding	IEP	Predicted GO
MF	GO:0008483	transaminase activity	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010639	negative regulation of organelle organization	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016769	transferase activity, transferring nitrogenous groups	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Predicted GO
BP	GO:0030490	maturation of SSU-rRNA	IEP	Predicted GO
MF	GO:0030515	snoRNA binding	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033043	regulation of organelle organization	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
BP	GO:0043086	negative regulation of catalytic activity	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0044092	negative regulation of molecular function	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0051052	regulation of DNA metabolic process	IEP	Predicted GO
BP	GO:0051095	regulation of helicase activity	IEP	Predicted GO
BP	GO:0051097	negative regulation of helicase activity	IEP	Predicted GO
BP	GO:0051129	negative regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051336	regulation of hydrolase activity	IEP	Predicted GO
BP	GO:0051346	negative regulation of hydrolase activity	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Predicted GO
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Predicted GO
BP	GO:1905774	regulation of DNA helicase activity	IEP	Predicted GO
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO
BP	GO:2001251	negative regulation of chromosome organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR027925	MCM_N	135	222
IPR033762	MCM_OB	236	365
IPR001208	MCM_dom	423	645

External Links

No external refs found!

At2g16440

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation