At4g02070

Description : DNA mismatch repair protein MSH6 [Source:UniProtKB/Swiss-Prot;Acc:O04716]

Gene families : OG_42_0001047 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001047_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Arabidopsis release: At4g02070
Cluster	HCCA clusters: Cluster_131

Target	Alias	Description	ECC score	Gene Family Method	Actions
evm.model.tig00000489.16	No alias	(at4g02070 : 188.0) encodes a DNA mismatch repair...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	InterProScan predictions
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000278	mitotic cell cycle	IEP	Predicted GO
CC	GO:0000775	chromosome, centromeric region	IEP	Predicted GO
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0003777	microtubule motor activity	IEP	Predicted GO
MF	GO:0003916	DNA topoisomerase activity	IEP	Predicted GO
MF	GO:0004014	adenosylmethionine decarboxylase activity	IEP	Predicted GO
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005089	Rho guanyl-nucleotide exchange factor activity	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
BP	GO:0006265	DNA topological change	IEP	Predicted GO
BP	GO:0006479	protein methylation	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Predicted GO
BP	GO:0006595	polyamine metabolic process	IEP	Predicted GO
BP	GO:0006596	polyamine biosynthetic process	IEP	Predicted GO
BP	GO:0006597	spermine biosynthetic process	IEP	Predicted GO
BP	GO:0006914	autophagy	IEP	Predicted GO
BP	GO:0006928	movement of cell or subcellular component	IEP	Predicted GO
BP	GO:0007017	microtubule-based process	IEP	Predicted GO
BP	GO:0007018	microtubule-based movement	IEP	Predicted GO
BP	GO:0007049	cell cycle	IEP	Predicted GO
MF	GO:0008017	microtubule binding	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008170	N-methyltransferase activity	IEP	Predicted GO
BP	GO:0008213	protein alkylation	IEP	Predicted GO
BP	GO:0008215	spermine metabolic process	IEP	Predicted GO
BP	GO:0008216	spermidine metabolic process	IEP	Predicted GO
MF	GO:0008276	protein methyltransferase activity	IEP	Predicted GO
BP	GO:0008295	spermidine biosynthetic process	IEP	Predicted GO
BP	GO:0009309	amine biosynthetic process	IEP	Predicted GO
MF	GO:0015631	tubulin binding	IEP	Predicted GO
MF	GO:0016278	lysine N-methyltransferase activity	IEP	Predicted GO
MF	GO:0016279	protein-lysine N-methyltransferase activity	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
BP	GO:0016571	histone methylation	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0017048	Rho GTPase binding	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
BP	GO:0018022	peptidyl-lysine methylation	IEP	Predicted GO
MF	GO:0018024	histone-lysine N-methyltransferase activity	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
BP	GO:0034968	histone lysine methylation	IEP	Predicted GO
MF	GO:0042054	histone methyltransferase activity	IEP	Predicted GO
BP	GO:0042401	cellular biogenic amine biosynthetic process	IEP	Predicted GO
BP	GO:0044106	cellular amine metabolic process	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
BP	GO:0061919	process utilizing autophagic mechanism	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
BP	GO:0097164	ammonium ion metabolic process	IEP	Predicted GO
CC	GO:0098687	chromosomal region	IEP	Predicted GO
CC	GO:1902554	serine/threonine protein kinase complex	IEP	Predicted GO
CC	GO:1902911	protein kinase complex	IEP	Predicted GO
CC	GO:1990316	Atg1/ULK1 kinase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR007861	DNA_mismatch_repair_MutS_clamp	886	976
IPR000432	DNA_mismatch_repair_MutS_C	1080	1270
IPR007696	DNA_mismatch_repair_MutS_core	701	1017
IPR007860	DNA_mmatch_repair_MutS_con_dom	506	667
IPR007695	DNA_mismatch_repair_MutS-lik_N	380	495

External Links

No external refs found!

At4g02070

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation