Seita.2G322200.1

Description : Nonsense-Mediated mRNA Decay effector protein *(UPF1)

Gene families : OG_42_0003239 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003239_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Setaria italica: Seita.2G322200.1
Cluster	HCAA Clusters: Cluster_187

Target	Alias	Description	ECC score	Gene Family Method
Bradi1g27027	No alias	RNA helicase, putative	0.06	Orthogroups_2024-Update
Cre01.g040379	No alias	RNA helicase, putative	0.03	Orthogroups_2024-Update
Cre02.g092500	No alias	RNA helicase, putative	0.02	Orthogroups_2024-Update
GRMZM2G035020	No alias	RNA helicase, putative	0.03	Orthogroups_2024-Update
GRMZM2G138230	No alias	RNA helicase, putative	0.03	Orthogroups_2024-Update
PSME_00007711-RA	No alias	(at5g47010 : 1723.0) Required for nonsense-mediated mRNA...	0.02	Orthogroups_2024-Update
evm.model.contig_707.2	No alias	(at5g47010 : 1048.0) Required for nonsense-mediated mRNA...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
BP	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEA	16Dec
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	16Dec
MF	GO:0003723	RNA binding	IEA	16Dec
MF	GO:0003724	RNA helicase activity	IEA	16Dec
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004386	helicase activity	IEA	16Dec
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	16Dec
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	16Dec
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006401	RNA catabolic process	None	Extended
BP	GO:0006402	mRNA catabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	16Dec
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016071	mRNA metabolic process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	IEA	16Dec
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019439	aromatic compound catabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034655	nucleobase-containing compound catabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044270	cellular nitrogen compound catabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046700	heterocycle catabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901361	organic cyclic compound catabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0004197	cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
BP	GO:0010921	regulation of phosphatase activity	IEP	Predicted GO
BP	GO:0016579	protein deubiquitination	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
BP	GO:0019220	regulation of phosphate metabolic process	IEP	Predicted GO
MF	GO:0019783	ubiquitin-like protein-specific protease activity	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
MF	GO:0019902	phosphatase binding	IEP	Predicted GO
MF	GO:0019903	protein phosphatase binding	IEP	Predicted GO
BP	GO:0031399	regulation of protein modification process	IEP	Predicted GO
BP	GO:0032268	regulation of cellular protein metabolic process	IEP	Predicted GO
BP	GO:0035303	regulation of dephosphorylation	IEP	Predicted GO
BP	GO:0035304	regulation of protein dephosphorylation	IEP	Predicted GO
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:0043666	regulation of phosphoprotein phosphatase activity	IEP	Predicted GO
BP	GO:0050790	regulation of catalytic activity	IEP	Predicted GO
BP	GO:0051174	regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0051246	regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051336	regulation of hydrolase activity	IEP	Predicted GO
BP	GO:0065009	regulation of molecular function	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070646	protein modification by small protein removal	IEP	Predicted GO
MF	GO:0101005	ubiquitinyl hydrolase activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006935	Helicase/UvrB_N	520	580
IPR018999	RNA-helicase_UPF1_UPF2-interct	160	313

External Links

No external refs found!

Seita.2G322200.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation