Seita.9G444800.1

Description : component *(TOP6A) of somatic DNA topoisomerase VI complex

Gene families : OG_42_0001606 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001606_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Setaria italica: Seita.9G444800.1
Cluster	HCAA Clusters: Cluster_225

Target	Alias	Description	ECC score	Gene Family Method	Actions
Cre02.g084800	No alias	Spo11/DNA topoisomerase VI, subunit A protein	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	16Dec
MF	GO:0003824	catalytic activity	IEA	16Dec
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	16Dec
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	16Dec
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	IEA	16Dec
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000726	non-recombinational repair	IEP	Predicted GO
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004590	orotidine-5'-phosphate decarboxylase activity	IEP	Predicted GO
BP	GO:0006177	GMP biosynthetic process	IEP	Predicted GO
BP	GO:0006206	pyrimidine nucleobase metabolic process	IEP	Predicted GO
BP	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006303	double-strand break repair via nonhomologous end joining	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0008270	zinc ion binding	IEP	Predicted GO
MF	GO:0008483	transaminase activity	IEP	Predicted GO
BP	GO:0009112	nucleobase metabolic process	IEP	Predicted GO
BP	GO:0009116	nucleoside metabolic process	IEP	Predicted GO
BP	GO:0009119	ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0009163	nucleoside biosynthetic process	IEP	Predicted GO
MF	GO:0016769	transferase activity, transferring nitrogenous groups	IEP	Predicted GO
MF	GO:0016831	carboxy-lyase activity	IEP	Predicted GO
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Predicted GO
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019856	pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0032392	DNA geometric change	IEP	Predicted GO
BP	GO:0032508	DNA duplex unwinding	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
BP	GO:0042278	purine nucleoside metabolic process	IEP	Predicted GO
BP	GO:0042451	purine nucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0046037	GMP metabolic process	IEP	Predicted GO
BP	GO:0046112	nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0046128	purine ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0046129	purine ribonucleoside biosynthetic process	IEP	Predicted GO
MF	GO:0046872	metal ion binding	IEP	Predicted GO
MF	GO:0046914	transition metal ion binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901657	glycosyl compound metabolic process	IEP	Predicted GO
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013049	Spo11/TopoVI_A_N	152	213

External Links

No external refs found!

Seita.9G444800.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation