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GO:0003712: transcription coregulator activity (Molecular function)

"A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator]


There are 8530 sequences with this label.



Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_168 Chlamydomonas reinhardtii 6.12 % 7e-06 9.9e-05
Cluster_142 Klebsormidium nitens 50.0 % 0.001851 0.019741
Cluster_137 Picea abies 1.6 % 0.000459 0.00614
Cluster_1 Picea abies 0.97 % 0.001249 0.039704
Cluster_91 Porphyridium purpureum 50.0 % 0.002871 0.034448
Cluster_13 Selaginella moellendorffii 1.89 % 3.4e-05 0.001406
Cluster_706 Pseudotsuga menziesii 50.0 % 0.002117 0.016231
Cluster_121 Pseudotsuga menziesii 2.63 % 0.002963 0.018154
Cluster_7 Brachypodium distachyon 1.97 % 1.9e-05 0.000255
Cluster_98 Glycine max 2.0 % 0.000352 0.005199
Cluster_165 Zea mays 2.44 % 0.001124 0.014756
cluster_0076 Oryza sativa 0.74 % 0.000151 0.00387
Cluster_219 Sorghum bicolor 2.44 % 0.001053 0.040031
Cluster_167 Sorghum bicolor 2.83 % 3.2e-05 0.001917
Cluster_76 Setaria italica 2.68 % 1.8e-05 0.001724
Sequences (8530) (download table)



Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !