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GO:0008534: oxidized purine nucleobase lesion DNA N-glycosylase activity (Molecular function)

"Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296]


There are 661 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_3 Porphyridium purpureum 0.48 % 0.024776 0.048773
Cluster_409 Glycine max 0.54 % 0.00348 0.025717
Cluster_16 Zea mays 0.59 % 0.002662 0.033544
Cluster_244 Brassica rapa 1.37 % 0.001803 0.029261
Cluster_11 Sorghum bicolor 0.91 % 0.003223 0.039938
Cluster_308 Setaria italica 50.0 % 5.8e-05 0.001128
Sequences (661) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms