Description : (at4g34640 : 234.0) Encodes squalene synthase, which converts two molecules of farnesyl diphosphate (FPP) into squalene via an intermediate: presqualene diphosphate (PSPP). It is generally thought to be one of the key enzymes of sterol biosynthesis, since it catalyzes the first pathway-specific reaction of the sterol branch of the isoprenoid pathway.; squalene synthase 1 (SQS1); FUNCTIONS IN: farnesyl-diphosphate farnesyltransferase activity; INVOLVED IN: sterol biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Squalene/phytoene synthase, conserved site (InterPro:IPR019845), Terpenoid synthase (InterPro:IPR008949), Farnesyl-diphosphate farnesyltransferase (InterPro:IPR006449), Squalene/phytoene synthase (InterPro:IPR002060); BEST Arabidopsis thaliana protein match is: squalene synthase 2 (TAIR:AT4G34650.1); Has 1469 Blast hits to 1468 proteins in 521 species: Archae - 28; Bacteria - 581; Metazoa - 114; Fungi - 174; Plants - 415; Viruses - 0; Other Eukaryotes - 157 (source: NCBI BLink). & (reliability: 468.0) & (original description: no original description)
Condition specificity: 11 h after light (SPM: 0.36, entropy: 2.46, tau: 0.22)