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  5. evm.model.tig00001107.11

evm.model.tig00001107.11


Description : (at4g34640 : 234.0) Encodes squalene synthase, which converts two molecules of farnesyl diphosphate (FPP) into squalene via an intermediate: presqualene diphosphate (PSPP). It is generally thought to be one of the key enzymes of sterol biosynthesis, since it catalyzes the first pathway-specific reaction of the sterol branch of the isoprenoid pathway.; squalene synthase 1 (SQS1); FUNCTIONS IN: farnesyl-diphosphate farnesyltransferase activity; INVOLVED IN: sterol biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Squalene/phytoene synthase, conserved site (InterPro:IPR019845), Terpenoid synthase (InterPro:IPR008949), Farnesyl-diphosphate farnesyltransferase (InterPro:IPR006449), Squalene/phytoene synthase (InterPro:IPR002060); BEST Arabidopsis thaliana protein match is: squalene synthase 2 (TAIR:AT4G34650.1); Has 1469 Blast hits to 1468 proteins in 521 species: Archae - 28; Bacteria - 581; Metazoa - 114; Fungi - 174; Plants - 415; Viruses - 0; Other Eukaryotes - 157 (source: NCBI BLink). & (reliability: 468.0) & (original description: no original description)


Gene families : OG_42_0003316 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003316_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00001107.11
Cluster HCCA clusters: Cluster_154

Target Alias Description ECC score Gene Family Method Actions
Sobic.001G049600.1 No alias squalene synthase & EC_2.5 transferase transferring... 0.01 Orthogroups_2024-Update
Solyc10g054130 No alias Squalene synthase (AHRD V3.3 *** FDFT_NICBE) 0.01 Orthogroups_2024-Update
Sopen10g029700 No alias Squalene/phytoene synthase 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0000149 SNARE binding IEP Predicted GO
BP GO:0000226 microtubule cytoskeleton organization IEP Predicted GO
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0003924 GTPase activity IEP Predicted GO
MF GO:0005048 signal sequence binding IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
BP GO:0006367 transcription initiation from RNA polymerase II promoter IEP Predicted GO
BP GO:0006405 RNA export from nucleus IEP Predicted GO
BP GO:0006406 mRNA export from nucleus IEP Predicted GO
BP GO:0006605 protein targeting IEP Predicted GO
BP GO:0006612 protein targeting to membrane IEP Predicted GO
BP GO:0006613 cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006621 protein retention in ER lumen IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0007010 cytoskeleton organization IEP Predicted GO
BP GO:0007051 spindle organization IEP Predicted GO
MF GO:0008047 enzyme activator activity IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
MF GO:0008312 7S RNA binding IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0015931 nucleobase-containing compound transport IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016255 attachment of GPI anchor to protein IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
BP GO:0016973 poly(A)+ mRNA export from nucleus IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
MF GO:0019905 syntaxin binding IEP Predicted GO
BP GO:0022402 cell cycle process IEP Predicted GO
MF GO:0030695 GTPase regulator activity IEP Predicted GO
BP GO:0032507 maintenance of protein location in cell IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0032774 RNA biosynthetic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
MF GO:0033218 amide binding IEP Predicted GO
BP GO:0033365 protein localization to organelle IEP Predicted GO
BP GO:0034613 cellular protein localization IEP Predicted GO
BP GO:0035437 maintenance of protein localization in endoplasmic reticulum IEP Predicted GO
MF GO:0042277 peptide binding IEP Predicted GO
BP GO:0042592 homeostatic process IEP Predicted GO
CC GO:0042765 GPI-anchor transamidase complex IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045047 protein targeting to ER IEP Predicted GO
BP GO:0045185 maintenance of protein location IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
MF GO:0046923 ER retention sequence binding IEP Predicted GO
CC GO:0048500 signal recognition particle IEP Predicted GO
BP GO:0050657 nucleic acid transport IEP Predicted GO
BP GO:0050658 RNA transport IEP Predicted GO
BP GO:0051028 mRNA transport IEP Predicted GO
BP GO:0051168 nuclear export IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051225 spindle assembly IEP Predicted GO
BP GO:0051235 maintenance of location IEP Predicted GO
BP GO:0051236 establishment of RNA localization IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0051651 maintenance of location in cell IEP Predicted GO
MF GO:0060589 nucleoside-triphosphatase regulator activity IEP Predicted GO
BP GO:0065008 regulation of biological quality IEP Predicted GO
CC GO:0070652 HAUS complex IEP Predicted GO
BP GO:0070727 cellular macromolecule localization IEP Predicted GO
BP GO:0070925 organelle assembly IEP Predicted GO
BP GO:0070972 protein localization to endoplasmic reticulum IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0072594 establishment of protein localization to organelle IEP Predicted GO
BP GO:0072595 maintenance of protein localization in organelle IEP Predicted GO
BP GO:0072599 establishment of protein localization to endoplasmic reticulum IEP Predicted GO
BP GO:0072657 protein localization to membrane IEP Predicted GO
BP GO:0090150 establishment of protein localization to membrane IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!