Aliases : kfl00057_0130_v1.1
Description : (at5g58220 : 173.0) Encodes a transthyretin-like S-allantoin synthase protein that catalyzes two steps in the allantoin biosynthesis pathway by acting as a hydroxyisourate hydrolase and a 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) decarboxylase. Two alternatively spliced versions of the transcript give rise to a longer peroxisomally-targeted protein (AT5G58220.1 (called TTL1-)) and a slightly shorter cytoplasmic protein (AT5G58220.3 (called TTL2-)). Both have roughly equivalent enzymatic activity in vitro, but, allantoin biosynthesis is believed to occur in the peroxisome suggesting that the cytosolic form may participate in a different process.; transthyretin-like protein (TTL); FUNCTIONS IN: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity, hydroxyisourate hydrolase activity; INVOLVED IN: regulation of cell growth by extracellular stimulus, brassinosteroid mediated signaling pathway, protein homotetramerization; LOCATED IN: cytosol, extrinsic to internal side of plasma membrane, peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Bifunctional hydroxyisourate hydrolase/2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR017129), Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR018020), Hydroxyisourate hydrolase (InterPro:IPR014306), Transthyretin/hydroxyisourate hydrolase (InterPro:IPR000895); Has 3236 Blast hits to 3236 proteins in 817 species: Archae - 6; Bacteria - 1906; Metazoa - 529; Fungi - 103; Plants - 58; Viruses - 0; Other Eukaryotes - 634 (source: NCBI BLink). & (reliability: 346.0) & (original description: no original description)
Condition specificity: 7 h after dark (SPM: 0.38, entropy: 2.63, tau: 0.29)