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Expression profile for PSME_00010718-RA (PSME_00010718-RA)

Attention: This gene has low abundance.

Description : (at4g22970 : 775.0) Encodes a separase (ESP), homologous to human and mouse separase protein. Separase is a capase family protease required for the release of sister chromatid cohesion during meiosis and mitosis. Arabidopsis separase contains a predicted 2Fe2S-ferredoxin domain that is not present in the proteins of other organisms. Also contains a putative EF-hand calcium binding domain. Mutant seeds exhibited embryo arrest at the globular stage. The endosperm also exhibited a weak titan-like phenotype. Transgenic plants expressing AESP RNA interference (RNAi) from the meiosis-specific DMC1 promoter exhibited alterations in chromosome segregation during meiosis I and II that resulted in polyads containing from one to eight microspores. Plays an essential role in embryo development. Required for the removal of cohesin from meiotic chromosomes and establishment of meiotic nuclear domains. This gene was also identified through the rsw4 mutant. Lines carrying recessive, temperature-sensitive mutations exhibit reduced anisotropic growth at 30 degrees Celsius. Microtubules and cellulose microfibrils are not depleted or disoriented in the mutants at the restrictive temperature.; homolog of separase (ESP); FUNCTIONS IN: peptidase activity; INVOLVED IN: meiotic chromosome separation, chromosome separation, embryo development ending in seed dormancy, positive regulation of sister chromatid cohesion, endosperm development; LOCATED IN: nucleus; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C50, separase (InterPro:IPR005314); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G28550.1). & (reliability: 1550.0) & (original description: no original description)

Condition specificity: 6 h after dark (SPM: 0.45, entropy: 1.46, tau: 0.11)
Tissue specificity: Midnight (SPM: 0.45, entropy: 1.46, tau: 0.11)
ZT time: ZT16-19 (SPM: 0.45, entropy: 1.46, tau: 0.11)