Mp6g05370.1

Description : DNA topoisomerase (TOP1)

Gene families : OG_42_0004287 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004287_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Marchantia polymorpha: Mp6g05370.1
Cluster	HCAA Clusters: Cluster_36

Target	Alias	Description	ECC score	Gene Family Method
145504	No alias	DNA topoisomerase 1 beta	0.02	Orthogroups_2024-Update
At5g55300	No alias	DNA topoisomerase I alpha [Source:UniProtKB/TrEMBL;Acc:F4K3F4]	0.03	Orthogroups_2024-Update
Bradi3g16920	No alias	DNA topoisomerase 1 beta	0.03	Orthogroups_2024-Update
Brara.B01330.1	No alias	DNA topoisomerase *(TOP1)	0.02	Orthogroups_2024-Update
MA_120434g0010	No alias	(at5g55300 : 828.0) Encodes a type-I DNA topoisomerase...	0.02	Orthogroups_2024-Update
PSME_00015793-RA	No alias	(at5g55300 : 762.0) Encodes a type-I DNA topoisomerase...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	16Dec
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I activity	IEA	16Dec
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	16Dec
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000155	phosphorelay sensor kinase activity	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
MF	GO:0004673	protein histidine kinase activity	IEP	Predicted GO
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
CC	GO:0016592	mediator complex	IEP	Predicted GO
MF	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR008336	TopoI_DNA-bd_euk	479	690
IPR025834	TopoI_C_dom	951	1020
IPR013500	TopoI_cat_euk	693	916

External Links

No external refs found!

Mp6g05370.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation