evm.model.tig00000025.1

Description : (at2g47000 : 429.0) Multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above.; ATP binding cassette subfamily B4 (ABCB4); FUNCTIONS IN: xenobiotic-transporting ATPase activity, ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: in 8 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 21 (TAIR:AT3G62150.1); Has 844144 Blast hits to 390751 proteins in 4168 species: Archae - 14748; Bacteria - 659498; Metazoa - 17847; Fungi - 13026; Plants - 10001; Viruses - 45; Other Eukaryotes - 128979 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 353.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 858.0) & (original description: no original description)

Gene families : OG_42_0000040 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000025.1
Cluster	HCCA clusters: Cluster_61

Target	Alias	Description	ECC score	Gene Family Method
230688	No alias	ATP binding cassette subfamily B19	0.02	Orthogroups_2024-Update
A4A49_02254	No alias	abc transporter b family member 11	0.02	Orthogroups_2024-Update
Bradi1g66290	No alias	P-glycoprotein 20	0.02	Orthogroups_2024-Update
Bradi2g17720	No alias	P-glycoprotein 11	0.01	Orthogroups_2024-Update
Bradi2g20177	No alias	P-glycoprotein 11	0.01	Orthogroups_2024-Update
Bradi2g47360	No alias	P-glycoprotein 11	0.01	Orthogroups_2024-Update
Glyma.01G016500	No alias	P-glycoprotein 2	0.02	Orthogroups_2024-Update
Glyma.06G139500	No alias	ATP binding cassette subfamily B19	0.02	Orthogroups_2024-Update
Glyma.13G142100	No alias	ATP binding cassette subfamily B1	0.01	Orthogroups_2024-Update
Glyma.17G041300	No alias	ATP binding cassette subfamily B4	0.01	Orthogroups_2024-Update
Glyma.17G259100	No alias	P-glycoprotein 13	0.02	Orthogroups_2024-Update
Glyma.19G016400	No alias	ABC transporter family protein	0.02	Orthogroups_2024-Update
HORVU3Hr1G117180.29	No alias	subfamily ABCB transporter	0.01	Orthogroups_2024-Update
LOC_Os08g45030	No alias	multidrug resistance protein, putative, expressed	0.01	Orthogroups_2024-Update
MA_10432169g0010	No alias	(at2g47000 : 1463.0) Multidrug resistance ...	0.01	Orthogroups_2024-Update
MA_14136g0010	No alias	(at2g39480 : 909.0) P-glycoprotein 6 (PGP6); FUNCTIONS...	0.01	Orthogroups_2024-Update
MA_18863g0010	No alias	(at2g47000 : 769.0) Multidrug resistance P-glycoprotein...	0.01	Orthogroups_2024-Update
MA_8945353g0010	No alias	(at3g28860 : 432.0) Belongs to the family of ATP-binding...	0.01	Orthogroups_2024-Update
PSME_00009725-RA	No alias	(at3g62150 : 766.0) P-glycoprotein 21 (PGP21); FUNCTIONS...	0.01	Orthogroups_2024-Update
PSME_00037733-RA	No alias	(at3g28345 : 1445.0) ABC transporter family protein;...	0.01	Orthogroups_2024-Update
PSME_00039275-RA	No alias	(at3g28345 : 1459.0) ABC transporter family protein;...	0.01	Orthogroups_2024-Update
Potri.014G113100	No alias	P-glycoprotein 11	0.02	Orthogroups_2024-Update
Potri.014G113200	No alias	P-glycoprotein 21	0.02	Orthogroups_2024-Update
Pp1s29_108V6	No alias	multidrug pheromone mdr abc transporter family	0.02	Orthogroups_2024-Update
Pp1s338_12V6	No alias	multidrug pheromone mdr abc transporter family	0.01	Orthogroups_2024-Update
Seita.5G031800.1	No alias	subfamily ABCB transporter	0.01	Orthogroups_2024-Update
Seita.6G253500.1	No alias	subfamily ABCB transporter	0.01	Orthogroups_2024-Update
Seita.9G449100.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
Solyc07g064120	No alias	ABC transporter B family protein (AHRD V3.3 *** G7JF16_MEDTR)	0.01	Orthogroups_2024-Update
Solyc11g067300	No alias	ABC transporter B family protein (AHRD V3.3 *** G7IBR0_MEDTR)	0.01	Orthogroups_2024-Update
Sopen02g032160	No alias	ABC transporter transmembrane region	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0004329	formate-tetrahydrofolate ligase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
BP	GO:0006464	cellular protein modification process	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
MF	GO:0008716	D-alanine-D-alanine ligase activity	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0015672	monovalent inorganic cation transport	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016851	magnesium chelatase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Predicted GO
MF	GO:0016881	acid-amino acid ligase activity	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0022406	membrane docking	IEP	Predicted GO
CC	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEP	Predicted GO
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0036211	protein modification process	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
BP	GO:0048278	vesicle docking	IEP	Predicted GO
MF	GO:0051002	ligase activity, forming nitrogen-metal bonds	IEP	Predicted GO
MF	GO:0051003	ligase activity, forming nitrogen-metal bonds, forming coordination complexes	IEP	Predicted GO
BP	GO:0051640	organelle localization	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
MF	GO:0071949	FAD binding	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
BP	GO:0140029	exocytic process	IEP	Predicted GO
BP	GO:0140056	organelle localization by membrane tethering	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1902600	proton transmembrane transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011527	ABC1_TM_dom	14	198
IPR011527	ABC1_TM_dom	694	768
IPR003439	ABC_transporter-like	287	439

External Links

No external refs found!

evm.model.tig00000025.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation