evm.model.tig00000093.110

Description : (at1g52500 : 88.2) Encodes one of the splice variants of Arabidopsis thaliana MutM homolog. Encodes a formamidopyrimidine-DNA glycosylase that has abasic lyase activity and is able to nick double- stranded oligonucleotides containing 8-oxo-7,8-dihydroguanine (8-oxoG) in vitro.; MUTM homolog-1 (MMH-1); CONTAINS InterPro DOMAIN/s: Ribosomal protein S13-like, H2TH (InterPro:IPR010979), DNA glycosylase/AP lyase, H2TH DNA-binding (InterPro:IPR015886), DNA glycosylase/AP lyase, catalytic domain (InterPro:IPR012319), DNA glycosylase/AP lyase (InterPro:IPR000191); Has 11102 Blast hits to 10156 proteins in 2240 species: Archae - 10; Bacteria - 5065; Metazoa - 1812; Fungi - 570; Plants - 321; Viruses - 42; Other Eukaryotes - 3282 (source: NCBI BLink). & (reliability: 176.4) & (original description: no original description)

Gene families : OG_42_0004977 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004977_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000093.110
Cluster	HCCA clusters: Cluster_122

Target	Alias	Description	ECC score	Gene Family Method	Actions
Solyc03g117510	No alias	Formamidopyrimidine-DNA glycosylase, putative (AHRD V3.3...	0.01	Orthogroups_2024-Update
Sopen03g036410	No alias	Formamidopyrimidine-DNA glycosylase H2TH domain	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	InterProScan predictions
BP	GO:0006289	nucleotide-excision repair	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	InterProScan predictions
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	None	Extended
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEA	InterProScan predictions
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001514	selenocysteine incorporation	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006417	regulation of translation	IEP	Predicted GO
BP	GO:0006451	translational readthrough	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
BP	GO:0010608	posttranscriptional regulation of gene expression	IEP	Predicted GO
BP	GO:0032268	regulation of cellular protein metabolic process	IEP	Predicted GO
BP	GO:0034248	regulation of cellular amide metabolic process	IEP	Predicted GO
BP	GO:0051246	regulation of protein metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR015886	DNA_glyclase/AP_lyase_DNA-bd	133	216
IPR012319	FPG_cat	3	110

External Links

No external refs found!

evm.model.tig00000093.110

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation