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  5. evm.model.tig00000144.9

evm.model.tig00000144.9


Description : (at1g68760 : 92.4) Encodes a cytosol-localized nudix hydrolase that hydrolyzes 8-oxo-(d)GTP to its monophosphate form. This protective mechanism prevents the misincorporation of these oxidized nucleotides into DNA and RNA. NUDX1 also has a low level of dihydroneopterin triphosphate pyrophosphatase activity in vitro and may participate in the folate synthesis pathway.; nudix hydrolase 1 (NUDX1); FUNCTIONS IN: hydrolase activity, dihydroneopterin triphosphate pyrophosphohydrolase activity, 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; INVOLVED IN: response to DNA damage stimulus; LOCATED IN: cytosol; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase (InterPro:IPR020476), NUDIX hydrolase, conserved site (InterPro:IPR020084), NUDIX hydrolase domain (InterPro:IPR000086); Has 6319 Blast hits to 6317 proteins in 1575 species: Archae - 191; Bacteria - 5327; Metazoa - 193; Fungi - 66; Plants - 51; Viruses - 14; Other Eukaryotes - 477 (source: NCBI BLink). & (reliability: 184.8) & (original description: no original description)


Gene families : OG_42_0008511 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0008511_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00000144.9
Cluster HCCA clusters: Cluster_83


Type GO Term Name Evidence Source
MF GO:0016787 hydrolase activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000002 mitochondrial genome maintenance IEP Predicted GO
BP GO:0000226 microtubule cytoskeleton organization IEP Predicted GO
CC GO:0000229 cytoplasmic chromosome IEP Predicted GO
CC GO:0000262 mitochondrial chromosome IEP Predicted GO
MF GO:0003697 single-stranded DNA binding IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
CC GO:0005815 microtubule organizing center IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
BP GO:0007005 mitochondrion organization IEP Predicted GO
BP GO:0007010 cytoskeleton organization IEP Predicted GO
BP GO:0007062 sister chromatid cohesion IEP Predicted GO
BP GO:0007064 mitotic sister chromatid cohesion IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008716 D-alanine-D-alanine ligase activity IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
BP GO:0016579 protein deubiquitination IEP Predicted GO
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Predicted GO
MF GO:0016881 acid-amino acid ligase activity IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
BP GO:0022402 cell cycle process IEP Predicted GO
CC GO:0031390 Ctf18 RFC-like complex IEP Predicted GO
BP GO:0034453 microtubule anchoring IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
BP GO:0044265 cellular macromolecule catabolic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044429 mitochondrial part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
BP GO:0051276 chromosome organization IEP Predicted GO
BP GO:0070646 protein modification by small protein removal IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:1903047 mitotic cell cycle process IEP Predicted GO
InterPro domains Description Start Stop
IPR000086 NUDIX_hydrolase_dom 8 122
No external refs found!