evm.model.tig00000194.21

Description : (at1g09830 : 392.0) glycinamide ribonucleotide synthetase (GAR synthetase) that catalyzes the conversion of phosphoribosyl amine to phosphoribosyl glycineamide; Glycinamide ribonucleotide (GAR) synthetase; FUNCTIONS IN: phosphoribosylamine-glycine ligase activity; INVOLVED IN: purine base biosynthetic process, purine nucleotide biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribosylglycinamide synthetase, conserved site (InterPro:IPR020559), Phosphoribosylglycinamide synthetase, C-domain (InterPro:IPR020560), Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (InterPro:IPR020561), ATP-grasp fold, subdomain 1 (InterPro:IPR013815), PreATP-grasp-like fold (InterPro:IPR016185), Phosphoribosylglycinamide synthetase, N-domain (InterPro:IPR020562), ATP-grasp fold (InterPro:IPR011761), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Pre-ATP-grasp fold (InterPro:IPR013817), Rudiment single hybrid motif (InterPro:IPR011054), Phosphoribosylglycinamide synthetase (InterPro:IPR000115); Has 12648 Blast hits to 12644 proteins in 2666 species: Archae - 340; Bacteria - 7373; Metazoa - 216; Fungi - 226; Plants - 88; Viruses - 0; Other Eukaryotes - 4405 (source: NCBI BLink). & (p52421|pur2_vigun : 255.0) Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase) (Fragment) - Vigna unguiculata (Cowpea) & (reliability: 784.0) & (original description: no original description)

Gene families : OG_42_0003875 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003875_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000194.21
Cluster	HCCA clusters: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
Kfl00357_0080	kfl00357_0080_v1.1	(at1g09830 : 602.0) glycinamide ribonucleotide...	0.02	Orthogroups_2024-Update
LOC_Os12g09540	No alias	phosphoribosylamine--glycine ligase, putative, expressed	0.01	Orthogroups_2024-Update
Mp4g18670.1	No alias	glycinamide RN synthetase (GARS)	0.03	Orthogroups_2024-Update
Sobic.009G214200.1	No alias	glycinamide RN synthetase *(GARS) & EC_6.3 ligase...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006144	purine nucleobase metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009112	nucleobase metabolic process	None	Extended
BP	GO:0009113	purine nucleobase biosynthetic process	IEA	InterProScan predictions
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042440	pigment metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046112	nucleobase biosynthetic process	None	Extended
BP	GO:0046148	pigment biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0000287	magnesium ion binding	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003724	RNA helicase activity	IEP	Predicted GO
MF	GO:0003883	CTP synthase activity	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0004004	ATP-dependent RNA helicase activity	IEP	Predicted GO
MF	GO:0004743	pyruvate kinase activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
MF	GO:0008026	ATP-dependent helicase activity	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008186	RNA-dependent ATPase activity	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
MF	GO:0030955	potassium ion binding	IEP	Predicted GO
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Predicted GO
MF	GO:0031420	alkali metal ion binding	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042255	ribosome assembly	IEP	Predicted GO
BP	GO:0042256	mature ribosome assembly	IEP	Predicted GO
MF	GO:0043021	ribonucleoprotein complex binding	IEP	Predicted GO
MF	GO:0043022	ribosome binding	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
MF	GO:0044877	protein-containing complex binding	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Predicted GO
BP	GO:0070925	organelle assembly	IEP	Predicted GO
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR020562	PRibGlycinamide_synth_N	116	215
IPR020560	PRibGlycinamide_synth_C-dom	444	471
IPR020561	PRibGlycinamid_synth_ATP-grasp	216	408

External Links

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evm.model.tig00000194.21

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation