evm.model.tig00000254.82

Description : (at1g63120 : 87.0) AtRBL2 has been identified as a rhomboid protein involved in regulated intramembrane proteolysis (RIP). The enzyme has the proteolytic activity and substrate specificity comparable to the Drosophila Rho-1 protein.; RHOMBOID-like 2 (RBL2); CONTAINS InterPro DOMAIN/s: Peptidase S54, rhomboid (InterPro:IPR002610); BEST Arabidopsis thaliana protein match is: RHOMBOID-like protein 6 (TAIR:AT1G12750.3); Has 6856 Blast hits to 6855 proteins in 1947 species: Archae - 152; Bacteria - 4411; Metazoa - 521; Fungi - 179; Plants - 374; Viruses - 0; Other Eukaryotes - 1219 (source: NCBI BLink). & (reliability: 174.0) & (original description: no original description)

Gene families : OG_42_0000533 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000533_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000254.82
Cluster	HCCA clusters: Cluster_161

Target	Alias	Description	ECC score	Gene Family Method
Bradi5g18750	No alias	RHOMBOID-like protein 6	0.01	Orthogroups_2024-Update
Brara.J02500.1	No alias	protease *(RBL)	0.02	Orthogroups_2024-Update
PSME_00043491-RA	No alias	(at2g29050 : 90.5) RHOMBOID-like 1 (RBL1); FUNCTIONS IN:...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004252	serine-type endopeptidase activity	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008236	serine-type peptidase activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0017171	serine hydrolase activity	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0044425	membrane part	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006479	protein methylation	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0008170	N-methyltransferase activity	IEP	Predicted GO
BP	GO:0008213	protein alkylation	IEP	Predicted GO
MF	GO:0008276	protein methyltransferase activity	IEP	Predicted GO
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Predicted GO
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Predicted GO
MF	GO:0016278	lysine N-methyltransferase activity	IEP	Predicted GO
MF	GO:0016279	protein-lysine N-methyltransferase activity	IEP	Predicted GO
BP	GO:0016569	covalent chromatin modification	IEP	Predicted GO
BP	GO:0016570	histone modification	IEP	Predicted GO
BP	GO:0016571	histone methylation	IEP	Predicted GO
BP	GO:0018022	peptidyl-lysine methylation	IEP	Predicted GO
MF	GO:0018024	histone-lysine N-methyltransferase activity	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018205	peptidyl-lysine modification	IEP	Predicted GO
MF	GO:0019829	cation-transporting ATPase activity	IEP	Predicted GO
MF	GO:0022853	active ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0030176	integral component of endoplasmic reticulum membrane	IEP	Predicted GO
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	IEP	Predicted GO
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
BP	GO:0034968	histone lysine methylation	IEP	Predicted GO
MF	GO:0035091	phosphatidylinositol binding	IEP	Predicted GO
MF	GO:0042054	histone methyltransferase activity	IEP	Predicted GO
MF	GO:0042625	ATPase coupled ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0043414	macromolecule methylation	IEP	Predicted GO
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	IEP	Predicted GO
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Predicted GO
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR022764	Peptidase_S54_rhomboid_dom	118	261

External Links

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evm.model.tig00000254.82

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation