evm.model.tig00000718.3

Description : (at3g13090 : 182.0) member of MRP subfamily; multidrug resistance-associated protein 8 (MRP8); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 7 (TAIR:AT3G13100.1); Has 618731 Blast hits to 341231 proteins in 4024 species: Archae - 11229; Bacteria - 503340; Metazoa - 11410; Fungi - 6818; Plants - 5765; Viruses - 13; Other Eukaryotes - 80156 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 89.7) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 364.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000718.3
Cluster	HCCA clusters: Cluster_15

Target	Alias	Description	ECC score	Gene Family Method
145432	No alias	multidrug resistance-associated protein 6	0.01	Orthogroups_2024-Update
169678	No alias	multidrug resistance-associated protein 6	0.03	Orthogroups_2024-Update
Cre17.g734612	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
Glyma.08G190700	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
Glyma.13G220000	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
Glyma.15G092400	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
Glyma.18G079700	No alias	multidrug resistance-associated protein 3	0.02	Orthogroups_2024-Update
Kfl00307_0100	kfl00307_0100_v1.1	(at2g07680 : 559.0) member of MRP subfamily; multidrug...	0.01	Orthogroups_2024-Update
Mp4g11930.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Pp1s224_120V6	No alias	multidrug resistance protein abc transporter family	0.02	Orthogroups_2024-Update
Pp1s342_31V6	No alias	multidrug resistance protein abc transporter family	0.01	Orthogroups_2024-Update
Seita.7G044400.1	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update
Sobic.003G160200.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
evm.model.contig_3396.7	No alias	(at2g34660 : 863.0) encodes a multidrug...	0.01	Orthogroups_2024-Update
evm.model.contig_4450.11	No alias	(at1g04120 : 712.0) encodes a high-affinity inositol...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
MF	GO:0008144	drug binding	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
MF	GO:0008565	protein transporter activity	IEP	Predicted GO
BP	GO:0008616	queuosine biosynthetic process	IEP	Predicted GO
BP	GO:0009119	ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0009163	nucleoside biosynthetic process	IEP	Predicted GO
MF	GO:0010181	FMN binding	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
MF	GO:0016211	ammonia ligase activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IEP	Predicted GO
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEP	Predicted GO
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Predicted GO
BP	GO:0017004	cytochrome complex assembly	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0030151	molybdenum ion binding	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
MF	GO:0032977	membrane insertase activity	IEP	Predicted GO
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
MF	GO:0042802	identical protein binding	IEP	Predicted GO
MF	GO:0042803	protein homodimerization activity	IEP	Predicted GO
BP	GO:0043094	cellular metabolic compound salvage	IEP	Predicted GO
BP	GO:0043174	nucleoside salvage	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
BP	GO:0046116	queuosine metabolic process	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
MF	GO:0051213	dioxygenase activity	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
MF	GO:0071949	FAD binding	IEP	Predicted GO
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Predicted GO
BP	GO:1990397	queuosine salvage	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	50	160

External Links

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evm.model.tig00000718.3

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation