Description : (at5g23630 : 453.0) A member of the eukaryotic type V subfamily (P5) of P-type ATPase cation pumps; MIA is most similar to the human P5 ATPase ATY2(44% identity) and to Spf1p from S. cerevisiae (41% identity). Highly abundant in the endoplasmic reticulum and small vesicles of developing pollen grains and tapetum cells. T-DNA insertional mutants of MIA suffer from imbalances in cation homeostasis and exhibit a severe reduction in fertility. Mutant microspores fail to separate from tetrads and pollen grains are fragile with an abnormal morphology and altered cell wall structure. MIA is also named PDR2 and was shown to be required for proper expression of SCARECROW (SCR), a key regulator of root patterning, and for stem-cell maintenance in Pi-deprived roots.; phosphate deficiency response 2 (PDR2); FUNCTIONS IN: cation-transporting ATPase activity; INVOLVED IN: in 6 processes; LOCATED IN: endoplasmic reticulum, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, unknown pump specificity (type V) (InterPro:IPR006544), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: calcium ATPase 2 (TAIR:AT4G37640.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 906.0) & (original description: no original description)
Gene families : OG_42_0005645 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005645_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00000806.13 | |
Cluster | HCCA clusters: Cluster_144 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
134300 | No alias | phosphate deficiency response 2 | 0.01 | Orthogroups_2024-Update | |
Kfl00235_0200 | kfl00235_0200_v1.1 | (at5g23630 : 1343.0) A member of the eukaryotic type V... | 0.01 | Orthogroups_2024-Update | |
MA_101231g0010 | No alias | (at5g23630 : 794.0) A member of the eukaryotic type V... | 0.03 | Orthogroups_2024-Update | |
Seita.3G249100.1 | No alias | P5-type cation-transporting ATPase *(MIA) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000123 | histone acetyltransferase complex | IEP | Predicted GO |
CC | GO:0000124 | SAGA complex | IEP | Predicted GO |
MF | GO:0000155 | phosphorelay sensor kinase activity | IEP | Predicted GO |
MF | GO:0003676 | nucleic acid binding | IEP | Predicted GO |
MF | GO:0003712 | transcription coregulator activity | IEP | Predicted GO |
MF | GO:0004312 | fatty acid synthase activity | IEP | Predicted GO |
MF | GO:0004318 | enoyl-[acyl-carrier-protein] reductase (NADH) activity | IEP | Predicted GO |
MF | GO:0004664 | prephenate dehydratase activity | IEP | Predicted GO |
MF | GO:0004673 | protein histidine kinase activity | IEP | Predicted GO |
MF | GO:0005216 | ion channel activity | IEP | Predicted GO |
MF | GO:0005230 | extracellular ligand-gated ion channel activity | IEP | Predicted GO |
MF | GO:0005488 | binding | IEP | Predicted GO |
MF | GO:0005524 | ATP binding | IEP | Predicted GO |
CC | GO:0005575 | cellular_component | IEP | Predicted GO |
BP | GO:0006558 | L-phenylalanine metabolic process | IEP | Predicted GO |
MF | GO:0008897 | holo-[acyl-carrier-protein] synthase activity | IEP | Predicted GO |
BP | GO:0009073 | aromatic amino acid family biosynthetic process | IEP | Predicted GO |
BP | GO:0009094 | L-phenylalanine biosynthetic process | IEP | Predicted GO |
BP | GO:0009095 | aromatic amino acid family biosynthetic process, prephenate pathway | IEP | Predicted GO |
MF | GO:0015267 | channel activity | IEP | Predicted GO |
MF | GO:0015276 | ligand-gated ion channel activity | IEP | Predicted GO |
CC | GO:0016021 | integral component of membrane | IEP | Predicted GO |
MF | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | IEP | Predicted GO |
MF | GO:0016775 | phosphotransferase activity, nitrogenous group as acceptor | IEP | Predicted GO |
MF | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups | IEP | Predicted GO |
MF | GO:0022803 | passive transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0022834 | ligand-gated channel activity | IEP | Predicted GO |
MF | GO:0022836 | gated channel activity | IEP | Predicted GO |
MF | GO:0022838 | substrate-specific channel activity | IEP | Predicted GO |
MF | GO:0022839 | ion gated channel activity | IEP | Predicted GO |
BP | GO:0030258 | lipid modification | IEP | Predicted GO |
MF | GO:0030554 | adenyl nucleotide binding | IEP | Predicted GO |
CC | GO:0031224 | intrinsic component of membrane | IEP | Predicted GO |
CC | GO:0031248 | protein acetyltransferase complex | IEP | Predicted GO |
MF | GO:0032559 | adenyl ribonucleotide binding | IEP | Predicted GO |
CC | GO:0042765 | GPI-anchor transamidase complex | IEP | Predicted GO |
MF | GO:0043167 | ion binding | IEP | Predicted GO |
CC | GO:0044425 | membrane part | IEP | Predicted GO |
BP | GO:0046488 | phosphatidylinositol metabolic process | IEP | Predicted GO |
BP | GO:0046834 | lipid phosphorylation | IEP | Predicted GO |
BP | GO:0046854 | phosphatidylinositol phosphorylation | IEP | Predicted GO |
CC | GO:0070461 | SAGA-type complex | IEP | Predicted GO |
MF | GO:0097159 | organic cyclic compound binding | IEP | Predicted GO |
MF | GO:1901363 | heterocyclic compound binding | IEP | Predicted GO |
BP | GO:1902221 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process | IEP | Predicted GO |
BP | GO:1902223 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process | IEP | Predicted GO |
CC | GO:1902493 | acetyltransferase complex | IEP | Predicted GO |
CC | GO:1902494 | catalytic complex | IEP | Predicted GO |
CC | GO:1905368 | peptidase complex | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |