evm.model.tig00000842.11

Description : (at1g17220 : 527.0) Encodes a chloroplast localized protein with similarity to translation initiation factor 2. Can complement loss of INFB in E.coli suggesting FUG1 does function as a translation initiation factor in vivo. Identified as a suppressor of the leaf variegation mutant var2-6. Suppression is only seen in hypomorphs as complete loss of function alleles are embryo lethal.; fu-gaeri1 (FUG1); FUNCTIONS IN: translation initiation factor activity; INVOLVED IN: translational initiation; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Translation initiation factor IF-2, N-terminal (InterPro:IPR006847), Small GTP-binding protein (InterPro:IPR005225), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Translation initiation factor 2 related (InterPro:IPR015760), Initiation factor 2 (InterPro:IPR000178), Protein synthesis factor, GTP-binding (InterPro:IPR000795), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: Translation initiation factor 2, small GTP-binding protein (TAIR:AT4G11160.1); Has 64472 Blast hits to 64325 proteins in 4737 species: Archae - 1215; Bacteria - 42273; Metazoa - 2198; Fungi - 2344; Plants - 1110; Viruses - 4; Other Eukaryotes - 15328 (source: NCBI BLink). & (p57997|if2c_phavu : 519.0) Translation initiation factor IF-2, chloroplast precursor (PvIF2cp) - Phaseolus vulgaris (Kidney bean) (French bean) & (reliability: 1054.0) & (original description: no original description)

Gene families : OG_42_0001965 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001965_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000842.11
Cluster	HCCA clusters: Cluster_79

Target	Alias	Description	ECC score	Gene Family Method
A4A49_19842	No alias	translation initiation factor if-2, chloroplastic	0.01	Orthogroups_2024-Update
At4g11160	No alias	At4g11160 [Source:UniProtKB/TrEMBL;Acc:Q67ZW2]	0.03	Orthogroups_2024-Update
Bradi2g38310	No alias	Translation initiation factor 2, small GTP-binding protein	0.01	Orthogroups_2024-Update
Cre07.g341850	No alias	Translation initiation factor 2, small GTP-binding protein	0.01	Orthogroups_2024-Update
Glyma.08G174200	No alias	Translation initiation factor 2, small GTP-binding protein	0.01	Orthogroups_2024-Update
Glyma.15G253000	No alias	Translation initiation factor 2, small GTP-binding protein	0.01	Orthogroups_2024-Update
Glyma.19G224000	No alias	Translation initiation factor 2, small GTP-binding protein	0.02	Orthogroups_2024-Update
LOC_Os05g49970	No alias	translation initiation factor IF-2, chloroplast...	0.02	Orthogroups_2024-Update
LOC_Os09g34010	No alias	expressed protein	0.02	Orthogroups_2024-Update
MA_4340g0010	No alias	(at1g17220 : 598.0) Encodes a chloroplast localized...	0.01	Orthogroups_2024-Update
Pp1s59_148V6	No alias	translation initiation factor if-2	0.02	Orthogroups_2024-Update
Pp1s77_109V6	No alias	translation initiation factor if-2	0.02	Orthogroups_2024-Update
Seita.1G380500.1	No alias	translation initiation factor *(IF-2)	0.01	Orthogroups_2024-Update
evm.model.contig_2347.7	No alias	(at4g11160 : 330.0) Translation initiation factor 2,...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003924	GTPase activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0004325	ferrochelatase activity	IEP	Predicted GO
MF	GO:0004512	inositol-3-phosphate synthase activity	IEP	Predicted GO
MF	GO:0004743	pyruvate kinase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
BP	GO:0005975	carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0006020	inositol metabolic process	IEP	Predicted GO
BP	GO:0006021	inositol biosynthetic process	IEP	Predicted GO
BP	GO:0006066	alcohol metabolic process	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006352	DNA-templated transcription, initiation	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006721	terpenoid metabolic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0006783	heme biosynthetic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
BP	GO:0008150	biological_process	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
MF	GO:0008536	Ran GTPase binding	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016114	terpenoid biosynthetic process	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016744	transferase activity, transferring aldehyde or ketonic groups	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Predicted GO
MF	GO:0016872	intramolecular lyase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016987	sigma factor activity	IEP	Predicted GO
MF	GO:0017016	Ras GTPase binding	IEP	Predicted GO
BP	GO:0019751	polyol metabolic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0030955	potassium ion binding	IEP	Predicted GO
MF	GO:0031267	small GTPase binding	IEP	Predicted GO
MF	GO:0031420	alkali metal ion binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0042168	heme metabolic process	IEP	Predicted GO
BP	GO:0042440	pigment metabolic process	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0046148	pigment biosynthetic process	IEP	Predicted GO
BP	GO:0046165	alcohol biosynthetic process	IEP	Predicted GO
BP	GO:0046173	polyol biosynthetic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051188	cofactor biosynthetic process	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Predicted GO
BP	GO:1901617	organic hydroxy compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR023115	TIF_IF2_dom3	626	728
IPR000795	TF_GTP-bd_dom	339	499

External Links

No external refs found!

evm.model.tig00000842.11

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation