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  5. evm.model.tig00000842.19

evm.model.tig00000842.19


Description : (at1g50240 : 182.0) The FUSED (FU) gene belongs to Ser/Thr protein kinase family and has a key role in the hedgehog signaling pathway known to control cell proliferation and patterning in fruit flies and humans . Arabidopsis thaliana genome has a single Fu gene. Cytokinesis-defective mutants, which we named two-in-one (tio), result from mutations in Arabidopsis Fu. Phenotypic analysis of tio mutants reveals an essential role for TIO in conventional modes of cytokinesis in plant meristems and during male gametogenesis. TIO is tightly localized to the midline of the nascent phragmoplast and remains associated with the expanding phragmoplast ring. This gene was previously annotated as two gene models, AT1G50230.1 and AT1G50240.1, however the experimental evidence exists (Oh et al, Current Biology, 2005) showing that these two models are in fact single gene, named FUSED.; FUSED (FU); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), 26S proteasome non-ATPase regulatory subunit 5 (InterPro:IPR019538), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: serine/threonine protein kinase 2 (TAIR:AT3G08720.2); Has 138334 Blast hits to 135590 proteins in 4834 species: Archae - 164; Bacteria - 15793; Metazoa - 51363; Fungi - 13983; Plants - 33508; Viruses - 544; Other Eukaryotes - 22979 (source: NCBI BLink). & (reliability: 364.0) & (original description: no original description)


Gene families : OG_42_0006166 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006166_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00000842.19
Cluster HCCA clusters: Cluster_124


Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000030 mannosyltransferase activity IEP Predicted GO
MF GO:0000339 RNA cap binding IEP Predicted GO
MF GO:0000340 RNA 7-methylguanosine cap binding IEP Predicted GO
MF GO:0001871 pattern binding IEP Predicted GO
MF GO:0003729 mRNA binding IEP Predicted GO
MF GO:0004133 glycogen debranching enzyme activity IEP Predicted GO
MF GO:0004134 4-alpha-glucanotransferase activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004521 endoribonuclease activity IEP Predicted GO
MF GO:0004525 ribonuclease III activity IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006298 mismatch repair IEP Predicted GO
MF GO:0016757 transferase activity, transferring glycosyl groups IEP Predicted GO
MF GO:0016758 transferase activity, transferring hexosyl groups IEP Predicted GO
MF GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters IEP Predicted GO
CC GO:0030176 integral component of endoplasmic reticulum membrane IEP Predicted GO
MF GO:0030246 carbohydrate binding IEP Predicted GO
MF GO:0030247 polysaccharide binding IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
CC GO:0031227 intrinsic component of endoplasmic reticulum membrane IEP Predicted GO
MF GO:0032296 double-stranded RNA-specific ribonuclease activity IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
MF GO:2001070 starch binding IEP Predicted GO
InterPro domains Description Start Stop
IPR000225 Armadillo 368 396
No external refs found!