evm.model.tig00001214.13

Description : (at5g26680 : 234.0) 5'-3' exonuclease family protein; FUNCTIONS IN: 5'-3' exonuclease activity, DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, N-terminal (InterPro:IPR002421), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G29630.2); Has 3563 Blast hits to 3243 proteins in 839 species: Archae - 284; Bacteria - 855; Metazoa - 643; Fungi - 727; Plants - 266; Viruses - 42; Other Eukaryotes - 746 (source: NCBI BLink). & (q9sxq6|fen1a_orysa : 231.0) Flap endonuclease 1a (EC 3.1.-.-) (OsFEN-1a) - Oryza sativa (Rice) & (reliability: 468.0) & (original description: no original description)

Gene families : OG_42_0004801 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004801_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00001214.13
Cluster	HCCA clusters: Cluster_54

Target	Alias	Description	ECC score	Gene Family Method
Brara.F02804.1	No alias	flap structure-specific endonuclease *(FEN1) & flap...	0.01	Orthogroups_2024-Update
Cre03.g145687	No alias	5\'-3\' exonuclease family protein	0.05	Orthogroups_2024-Update
Cre16.g670550	No alias	5\'-3\' exonuclease family protein	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000123	histone acetyltransferase complex	IEP	Predicted GO
MF	GO:0000149	SNARE binding	IEP	Predicted GO
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003924	GTPase activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005680	anaphase-promoting complex	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006401	RNA catabolic process	IEP	Predicted GO
BP	GO:0006473	protein acetylation	IEP	Predicted GO
BP	GO:0006475	internal protein amino acid acetylation	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	IEP	Predicted GO
BP	GO:0007088	regulation of mitotic nuclear division	IEP	Predicted GO
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Predicted GO
BP	GO:0008156	negative regulation of DNA replication	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009889	regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009892	negative regulation of metabolic process	IEP	Predicted GO
BP	GO:0010498	proteasomal protein catabolic process	IEP	Predicted GO
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010564	regulation of cell cycle process	IEP	Predicted GO
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Predicted GO
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IEP	Predicted GO
BP	GO:0016569	covalent chromatin modification	IEP	Predicted GO
BP	GO:0016570	histone modification	IEP	Predicted GO
BP	GO:0016573	histone acetylation	IEP	Predicted GO
BP	GO:0018205	peptidyl-lysine modification	IEP	Predicted GO
BP	GO:0018393	internal peptidyl-lysine acetylation	IEP	Predicted GO
BP	GO:0018394	peptidyl-lysine acetylation	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0019222	regulation of metabolic process	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
MF	GO:0019905	syntaxin binding	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
BP	GO:0031144	proteasome localization	IEP	Predicted GO
CC	GO:0031248	protein acetyltransferase complex	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0031503	protein-containing complex localization	IEP	Predicted GO
MF	GO:0031625	ubiquitin protein ligase binding	IEP	Predicted GO
CC	GO:0032299	ribonuclease H2 complex	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0033043	regulation of organelle organization	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Predicted GO
BP	GO:0033047	regulation of mitotic sister chromatid segregation	IEP	Predicted GO
BP	GO:0034629	cellular protein-containing complex localization	IEP	Predicted GO
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043543	protein acylation	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
MF	GO:0044389	ubiquitin-like protein ligase binding	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0048478	replication fork protection	IEP	Predicted GO
BP	GO:0051052	regulation of DNA metabolic process	IEP	Predicted GO
BP	GO:0051053	negative regulation of DNA metabolic process	IEP	Predicted GO
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051783	regulation of nuclear division	IEP	Predicted GO
BP	GO:0051983	regulation of chromosome segregation	IEP	Predicted GO
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	IEP	Predicted GO
BP	GO:0080090	regulation of primary metabolic process	IEP	Predicted GO
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Predicted GO
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Predicted GO
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Predicted GO
CC	GO:1902493	acetyltransferase complex	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
BP	GO:1905818	regulation of chromosome separation	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	Predicted GO
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006085	XPG_DNA_repair_N	1	65
IPR006086	XPG-I_dom	146	232

External Links

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evm.model.tig00001214.13

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation