evm.model.tig00001366.20


Description : (at3g19050 : 296.0) PHRAGMOPLAST ORIENTING KINESIN 2 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK2 constructs were broader than those for POK1; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls.; phragmoplast orienting kinesin 2 (POK2); FUNCTIONS IN: microtubule motor activity, ATP binding; INVOLVED IN: cytokinesis; EXPRESSED IN: root vascular system, primary root tip, lateral root primordium; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast orienting kinesin 1 (TAIR:AT3G17360.1); Has 204267 Blast hits to 80386 proteins in 3219 species: Archae - 3327; Bacteria - 35963; Metazoa - 90351; Fungi - 17822; Plants - 12667; Viruses - 746; Other Eukaryotes - 43391 (source: NCBI BLink). & (o23826|k125_tobac : 227.0) 125 kDa kinesin-related protein - Nicotiana tabacum (Common tobacco) & (reliability: 592.0) & (original description: no original description)


Gene families : OG_42_0000151 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000151_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00001366.20
Cluster HCCA clusters: Cluster_123

Target Alias Description ECC score Gene Family Method Actions
A4A49_12894 No alias kinesin-like protein kin-5d 0.01 Orthogroups_2024-Update
A4A49_33743 No alias kinesin-like protein kin-5b 0.01 Orthogroups_2024-Update
Bradi4g30490 No alias P-loop containing nucleoside triphosphate hydrolases... 0.01 Orthogroups_2024-Update
evm.model.tig00020553.131 No alias (p46869|fla10_chlre : 181.0) Kinesin-like protein FLA10... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003777 microtubule motor activity IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
BP GO:0007018 microtubule-based movement IEA InterProScan predictions
MF GO:0008017 microtubule binding IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000808 origin recognition complex IEP Predicted GO
MF GO:0004180 carboxypeptidase activity IEP Predicted GO
MF GO:0004185 serine-type carboxypeptidase activity IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
BP GO:0006298 mismatch repair IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
MF GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity IEP Predicted GO
MF GO:0017056 structural constituent of nuclear pore IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
MF GO:0070008 serine-type exopeptidase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR012444 DUF1647 879 962
IPR001752 Kinesin_motor_dom 34 358
No external refs found!