Description : (at3g19050 : 296.0) PHRAGMOPLAST ORIENTING KINESIN 2 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK2 constructs were broader than those for POK1; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls.; phragmoplast orienting kinesin 2 (POK2); FUNCTIONS IN: microtubule motor activity, ATP binding; INVOLVED IN: cytokinesis; EXPRESSED IN: root vascular system, primary root tip, lateral root primordium; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast orienting kinesin 1 (TAIR:AT3G17360.1); Has 204267 Blast hits to 80386 proteins in 3219 species: Archae - 3327; Bacteria - 35963; Metazoa - 90351; Fungi - 17822; Plants - 12667; Viruses - 746; Other Eukaryotes - 43391 (source: NCBI BLink). & (o23826|k125_tobac : 227.0) 125 kDa kinesin-related protein - Nicotiana tabacum (Common tobacco) & (reliability: 592.0) & (original description: no original description)
Gene families : OG_42_0000151 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000151_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00001366.20 | |
Cluster | HCCA clusters: Cluster_123 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_12894 | No alias | kinesin-like protein kin-5d | 0.01 | Orthogroups_2024-Update | |
A4A49_33743 | No alias | kinesin-like protein kin-5b | 0.01 | Orthogroups_2024-Update | |
Bradi4g30490 | No alias | P-loop containing nucleoside triphosphate hydrolases... | 0.01 | Orthogroups_2024-Update | |
evm.model.tig00020553.131 | No alias | (p46869|fla10_chlre : 181.0) Kinesin-like protein FLA10... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003777 | microtubule motor activity | IEA | InterProScan predictions |
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
BP | GO:0007018 | microtubule-based movement | IEA | InterProScan predictions |
MF | GO:0008017 | microtubule binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000808 | origin recognition complex | IEP | Predicted GO |
MF | GO:0004180 | carboxypeptidase activity | IEP | Predicted GO |
MF | GO:0004185 | serine-type carboxypeptidase activity | IEP | Predicted GO |
CC | GO:0005634 | nucleus | IEP | Predicted GO |
CC | GO:0005643 | nuclear pore | IEP | Predicted GO |
BP | GO:0006298 | mismatch repair | IEP | Predicted GO |
BP | GO:0006913 | nucleocytoplasmic transport | IEP | Predicted GO |
MF | GO:0009002 | serine-type D-Ala-D-Ala carboxypeptidase activity | IEP | Predicted GO |
MF | GO:0017056 | structural constituent of nuclear pore | IEP | Predicted GO |
MF | GO:0030983 | mismatched DNA binding | IEP | Predicted GO |
CC | GO:0043227 | membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0043231 | intracellular membrane-bounded organelle | IEP | Predicted GO |
BP | GO:0051169 | nuclear transport | IEP | Predicted GO |
MF | GO:0070008 | serine-type exopeptidase activity | IEP | Predicted GO |
No external refs found! |