evm.model.tig00001628.3


Description : (at1g63440 : 260.0) The Arabidopsis P-type ATPase HMA5 is involved in Cu detoxification. hma5 mutant plants exhibit Cu hypersensitivity, which is especially dramatic in roots where HMA5 is mostly expressed.; heavy metal atpase 5 (HMA5); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: detoxification of copper ion, response to copper ion; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121), ATPase, P type, cation/copper-transporter (InterPro:IPR006403), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), Heavy-metal-associated, conserved site (InterPro:IPR017969), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: copper-exporting ATPase / responsive-to-antagonist 1 / copper-transporting ATPase (RAN1) (TAIR:AT5G44790.1); Has 47061 Blast hits to 34034 proteins in 3459 species: Archae - 1020; Bacteria - 31793; Metazoa - 4958; Fungi - 2589; Plants - 1873; Viruses - 3; Other Eukaryotes - 4825 (source: NCBI BLink). & (reliability: 520.0) & (original description: no original description)


Gene families : OG_42_0000805 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000805_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00001628.3
Cluster HCCA clusters: Cluster_51

Target Alias Description ECC score Gene Family Method Actions
Kfl00630_0010 kfl00630_0010_v1.1 (at5g44790 : 890.0) ATP dependent copper transporter... 0.02 Orthogroups_2024-Update
PSME_00042099-RA No alias (at1g63440 : 233.0) The Arabidopsis P-type ATPase HMA5... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0030001 metal ion transport IEA InterProScan predictions
MF GO:0046872 metal ion binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004252 serine-type endopeptidase activity IEP Predicted GO
MF GO:0005044 scavenger receptor activity IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
CC GO:0009521 photosystem IEP Predicted GO
CC GO:0009522 photosystem I IEP Predicted GO
CC GO:0009538 photosystem I reaction center IEP Predicted GO
BP GO:0017013 protein flavinylation IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
MF GO:0038024 cargo receptor activity IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
MF GO:0071949 FAD binding IEP Predicted GO
InterPro domains Description Start Stop
IPR006121 HMA_dom 14 51
IPR006121 HMA_dom 107 162
IPR006121 HMA_dom 389 448
No external refs found!