Description : (p29618|cdc21_orysa : 233.0) Cell division control protein 2 homolog 1 (EC 2.7.11.22) - Oryza sativa (Rice) & (at3g48750 : 231.0) A-type cyclin-dependent kinase. Together with its specific inhibitor, the Kip-related protein, KRP2 they regulate the mitosis-to-endocycle transition during leaf development. Dominant negative mutations abolish cell division. Loss of function phenotype has reduced fertility with failure to transmit via pollen. Pollen development is arrested at the second mitotic division. Expression is regulated by environmental and chemical signals. Part of the promoter is responsible for expression in trichomes. Functions as a positive regulator of cell proliferation during development of the male gametophyte, embryo and endosperm. Phosphorylation of threonine 161 is required for activation of its associated kinase.; cell division control 2 (CDC2); FUNCTIONS IN: protein binding, protein kinase activity, cyclin-dependent protein kinase activity, kinase activity; INVOLVED IN: in 8 processes; LOCATED IN: in 6 components; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cyclin-dependent kinase B1;2 (TAIR:AT2G38620.2); Has 126125 Blast hits to 124135 proteins in 4221 species: Archae - 112; Bacteria - 14002; Metazoa - 46757; Fungi - 13170; Plants - 30525; Viruses - 484; Other Eukaryotes - 21075 (source: NCBI BLink). & (reliability: 440.0) & (original description: no original description)
Gene families : OG_42_0012676 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0012676_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00020528.7 | |
Cluster | HCCA clusters: Cluster_61 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004672 | protein kinase activity | IEA | InterProScan predictions |
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
BP | GO:0006468 | protein phosphorylation | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003676 | nucleic acid binding | IEP | Predicted GO |
MF | GO:0003899 | DNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
CC | GO:0005789 | endoplasmic reticulum membrane | IEP | Predicted GO |
BP | GO:0006351 | transcription, DNA-templated | IEP | Predicted GO |
MF | GO:0016757 | transferase activity, transferring glycosyl groups | IEP | Predicted GO |
MF | GO:0016758 | transferase activity, transferring hexosyl groups | IEP | Predicted GO |
MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
BP | GO:0032774 | RNA biosynthetic process | IEP | Predicted GO |
MF | GO:0034062 | 5'-3' RNA polymerase activity | IEP | Predicted GO |
CC | GO:0044432 | endoplasmic reticulum part | IEP | Predicted GO |
BP | GO:0097659 | nucleic acid-templated transcription | IEP | Predicted GO |
MF | GO:0097747 | RNA polymerase activity | IEP | Predicted GO |
No external refs found! |