evm.model.tig00020537.65


Description : (q5z987|atr_orysa : 139.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (at5g40820 : 127.0) Encodes a Arabidopsis ortholog of the ATR protein kinase that is involved in a wide range of responses to DNA damage and plays a central role in cell-cycle regulation. Dominant loss of function alleles identified as suppressors of ALS also exhibit increased tolerance to aluminum. This may be due to the inhibition of terminal differentiation of the root apex upon exposure to Al.; Ataxia telangiectasia-mutated and RAD3-related (ATR); FUNCTIONS IN: protein serine/threonine kinase activity, inositol or phosphatidylinositol kinase activity, binding, phosphotransferase activity, alcohol group as acceptor; INVOLVED IN: in 9 processes; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), UME (InterPro:IPR012993), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), Armadillo-type fold (InterPro:IPR016024), PIK-related kinase (InterPro:IPR014009), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), PIK-related kinase, FATC (InterPro:IPR003152); BEST Arabidopsis thaliana protein match is: ataxia-telangiectasia mutated (TAIR:AT3G48190.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 254.0) & (original description: no original description)


Gene families : OG_42_0007184 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007184_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00020537.65
Cluster HCCA clusters: Cluster_61

Target Alias Description ECC score Gene Family Method Actions
Bradi1g30007 No alias Ataxia telangiectasia-mutated and RAD3-related 0.01 Orthogroups_2024-Update
Glyma.10G284200 No alias Ataxia telangiectasia-mutated and RAD3-related 0.01 Orthogroups_2024-Update
evm.model.contig_468.4 No alias (at5g40820 : 342.0) Encodes a Arabidopsis ortholog of... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0004674 protein serine/threonine kinase activity IEA InterProScan predictions
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000148 1,3-beta-D-glucan synthase complex IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0000271 polysaccharide biosynthetic process IEP Predicted GO
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predicted GO
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predicted GO
BP GO:0000398 mRNA splicing, via spliceosome IEP Predicted GO
MF GO:0003843 1,3-beta-D-glucan synthase activity IEP Predicted GO
MF GO:0004181 metallocarboxypeptidase activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
BP GO:0005976 polysaccharide metabolic process IEP Predicted GO
BP GO:0006073 cellular glucan metabolic process IEP Predicted GO
BP GO:0006074 (1->3)-beta-D-glucan metabolic process IEP Predicted GO
BP GO:0006075 (1->3)-beta-D-glucan biosynthetic process IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
MF GO:0008270 zinc ion binding IEP Predicted GO
BP GO:0009250 glucan biosynthetic process IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
CC GO:0016020 membrane IEP Predicted GO
BP GO:0016579 protein deubiquitination IEP Predicted GO
MF GO:0017069 snRNA binding IEP Predicted GO
MF GO:0017070 U6 snRNA binding IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030623 U5 snRNA binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033692 cellular polysaccharide biosynthetic process IEP Predicted GO
MF GO:0035251 UDP-glucosyltransferase activity IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044042 glucan metabolic process IEP Predicted GO
BP GO:0044264 cellular polysaccharide metabolic process IEP Predicted GO
CC GO:0044459 plasma membrane part IEP Predicted GO
MF GO:0046527 glucosyltransferase activity IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0051273 beta-glucan metabolic process IEP Predicted GO
BP GO:0051274 beta-glucan biosynthetic process IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
BP GO:0070646 protein modification by small protein removal IEP Predicted GO
BP GO:0070647 protein modification by small protein conjugation or removal IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
CC GO:0098797 plasma membrane protein complex IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
CC GO:1902494 catalytic complex IEP Predicted GO
InterPro domains Description Start Stop
IPR012993 UME 947 1046
IPR003151 PIK-rel_kinase_FAT 1620 1707
IPR003151 PIK-rel_kinase_FAT 1539 1613
No external refs found!