evm.model.tig00020553.141

Description : (q43266|pcna_maize : 272.0) Proliferating cell nuclear antigen (PCNA) - Zea mays (Maize) & (at1g07370 : 265.0) Encodes putative proliferating cell nuclear antigen involved in cell cycle regulation.; proliferating cellular nuclear antigen 1 (PCNA1); CONTAINS InterPro DOMAIN/s: Proliferating cell nuclear antigen, PCNA (InterPro:IPR000730), Proliferating cell nuclear antigen, PCNA, C-terminal (InterPro:IPR022649), Proliferating cell nuclear antigen, PCNA, conserved site (InterPro:IPR022659), Proliferating cell nuclear antigen, PCNA, N-terminal (InterPro:IPR022648); BEST Arabidopsis thaliana protein match is: proliferating cell nuclear antigen 2 (TAIR:AT2G29570.1); Has 1857 Blast hits to 1845 proteins in 456 species: Archae - 391; Bacteria - 0; Metazoa - 315; Fungi - 169; Plants - 159; Viruses - 71; Other Eukaryotes - 752 (source: NCBI BLink). & (reliability: 530.0) & (original description: no original description)

Gene families : OG_42_0003307 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003307_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00020553.141
Cluster	HCCA clusters: Cluster_54

Target	Alias	Description	ECC score	Gene Family Method
A4A49_31983	No alias	proliferating cell nuclear antigen	0.02	Orthogroups_2024-Update
At1g07370	No alias	Proliferating cellular nuclear antigen 1...	0.03	Orthogroups_2024-Update
At2g29570	No alias	Proliferating cell nuclear antigen 2...	0.01	Orthogroups_2024-Update
Brara.E01344.1	No alias	sliding clamp protein *(PCNA)	0.03	Orthogroups_2024-Update
Brara.I05365.1	No alias	sliding clamp protein *(PCNA)	0.02	Orthogroups_2024-Update
Cre12.g515850	No alias	proliferating cellular nuclear antigen 1	0.08	Orthogroups_2024-Update
Glyma.08G334900	No alias	proliferating cell nuclear antigen 2	0.05	Orthogroups_2024-Update
Glyma.18G067800	No alias	proliferating cell nuclear antigen 2	0.04	Orthogroups_2024-Update
Kfl00075_0310	kfl00075_0310_v1.1	(p22177\|pcna_soybn : 320.0) Proliferating cell nuclear...	0.06	Orthogroups_2024-Update
Kfl00114_0110	kfl00114_0110_v1.1	(p17070\|pcna_orysa : 408.0) Proliferating cell nuclear...	0.05	Orthogroups_2024-Update
LOC_Os02g56130	No alias	PCNA - Putative DNA replicative polymerase clamp, expressed	0.01	Orthogroups_2024-Update
MA_83835g0010	No alias	(p24314\|pcna_catro : 478.0) Proliferating cell nuclear...	0.02	Orthogroups_2024-Update
Mp2g02690.1	No alias	sliding clamp protein (PCNA)	0.01	Orthogroups_2024-Update
PSME_00038031-RA	No alias	(p24314\|pcna_catro : 479.0) Proliferating cell nuclear...	0.03	Orthogroups_2024-Update
Potri.009G040900	No alias	proliferating cell nuclear antigen 2	0.02	Orthogroups_2024-Update
Seita.1G356900.1	No alias	sliding clamp protein *(PCNA)	0.03	Orthogroups_2024-Update
Solyc06g076660	No alias	proliferating cell nuclear antigen	0.08	Orthogroups_2024-Update
evm.model.contig_3475.3	No alias	(q00268\|pcna1_dauca : 227.0) Proliferating cell nuclear...	0.09	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006275	regulation of DNA replication	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0003896	DNA primase activity	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Predicted GO
MF	GO:0004797	thymidine kinase activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005680	anaphase-promoting complex	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006231	dTMP biosynthetic process	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006298	mismatch repair	IEP	Predicted GO
BP	GO:0006310	DNA recombination	IEP	Predicted GO
BP	GO:0006401	RNA catabolic process	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0007088	regulation of mitotic nuclear division	IEP	Predicted GO
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
BP	GO:0008156	negative regulation of DNA replication	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009892	negative regulation of metabolic process	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0010498	proteasomal protein catabolic process	IEP	Predicted GO
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010564	regulation of cell cycle process	IEP	Predicted GO
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0019136	deoxynucleoside kinase activity	IEP	Predicted GO
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Predicted GO
MF	GO:0019206	nucleoside kinase activity	IEP	Predicted GO
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
BP	GO:0031144	proteasome localization	IEP	Predicted GO
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0031503	protein-containing complex localization	IEP	Predicted GO
MF	GO:0031625	ubiquitin protein ligase binding	IEP	Predicted GO
CC	GO:0032299	ribonuclease H2 complex	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
BP	GO:0033043	regulation of organelle organization	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Predicted GO
BP	GO:0033047	regulation of mitotic sister chromatid segregation	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0034629	cellular protein-containing complex localization	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
MF	GO:0044389	ubiquitin-like protein ligase binding	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0046073	dTMP metabolic process	IEP	Predicted GO
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0048478	replication fork protection	IEP	Predicted GO
MF	GO:0050797	thymidylate synthase (FAD) activity	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051053	negative regulation of DNA metabolic process	IEP	Predicted GO
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0051783	regulation of nuclear division	IEP	Predicted GO
BP	GO:0051983	regulation of chromosome segregation	IEP	Predicted GO
BP	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Predicted GO
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Predicted GO
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Predicted GO
BP	GO:1905818	regulation of chromosome separation	IEP	Predicted GO
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	Predicted GO
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR022648	Pr_cel_nuc_antig_N	1	123
IPR022649	Pr_cel_nuc_antig_C	127	263

External Links

No external refs found!

evm.model.tig00020553.141

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation