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  5. evm.model.tig00020553.158

evm.model.tig00020553.158


Description : (at4g30870 : 85.9) Encodes an Arabidopsis homolog of the endonuclease MSU81. T-DNA insertion lines of AtMSU81 have a deficiency in homologous recombination in somatic cells but only after genotoxic stress. Crosses with a hyperrecombinogenic mutant of the AtRecQ4A helicase resulted in synthetic lethality in the double mutant.; MMS AND UV SENSITIVE 81 (MUS81); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Restriction endonuclease, type II-like (InterPro:IPR011335); BEST Arabidopsis thaliana protein match is: Restriction endonuclease, type II-like superfamily protein (TAIR:AT5G39770.1); Has 631 Blast hits to 481 proteins in 192 species: Archae - 11; Bacteria - 4; Metazoa - 158; Fungi - 249; Plants - 48; Viruses - 0; Other Eukaryotes - 161 (source: NCBI BLink). & (reliability: 171.8) & (original description: no original description)


Gene families : OG_42_0005044 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005044_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00020553.158
Cluster HCCA clusters: Cluster_83

Target Alias Description ECC score Gene Family Method Actions
LOC_Os01g71960 No alias endonuclease, putative, expressed 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0004518 nuclease activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004190 aspartic-type endopeptidase activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0005227 calcium activated cation channel activity IEP Predicted GO
MF GO:0005261 cation channel activity IEP Predicted GO
MF GO:0005267 potassium channel activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006813 potassium ion transport IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0015079 potassium ion transmembrane transporter activity IEP Predicted GO
MF GO:0015269 calcium-activated potassium channel activity IEP Predicted GO
MF GO:0016286 small conductance calcium-activated potassium channel activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
CC GO:0019773 proteasome core complex, alpha-subunit complex IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
BP GO:0030030 cell projection organization IEP Predicted GO
BP GO:0030031 cell projection assembly IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
CC GO:0034464 BBSome IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043015 gamma-tubulin binding IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
CC GO:0044441 ciliary part IEP Predicted GO
CC GO:0044463 cell projection part IEP Predicted GO
BP GO:0044782 cilium organization IEP Predicted GO
BP GO:0051259 protein complex oligomerization IEP Predicted GO
BP GO:0051260 protein homooligomerization IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
BP GO:0060271 cilium assembly IEP Predicted GO
MF GO:0070001 aspartic-type peptidase activity IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
BP GO:0070925 organelle assembly IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
BP GO:0120031 plasma membrane bounded cell projection assembly IEP Predicted GO
BP GO:0120036 plasma membrane bounded cell projection organization IEP Predicted GO
CC GO:0120038 plasma membrane bounded cell projection part IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
InterPro domains Description Start Stop
IPR006166 ERCC4_domain 326 407
No external refs found!