evm.model.tig00020684.9

Description : (at1g30400 : 699.0) glutathione S-conjugate transporting ATPase (AtMRP1) mRNA. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.; ARABIDOPSIS THALIANA MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 (ATMRP1); FUNCTIONS IN: xenobiotic-transporting ATPase activity, ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: response to cyclopentenone; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 2 (TAIR:AT2G34660.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 137.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 1398.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00020684.9
Cluster	HCCA clusters: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method
267218	No alias	multidrug resistance-associated protein 14	0.01	Orthogroups_2024-Update
Bradi1g37826	No alias	multidrug resistance-associated protein 6	0.01	Orthogroups_2024-Update
Potri.011G091200	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
Solyc05g014390	No alias	ABC subfamily C transporter (AHRD V3.3 *** A0A077RXF4_WHEAT)	0.01	Orthogroups_2024-Update
Sopen01g032440	No alias	ABC transporter transmembrane region	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003941	L-serine ammonia-lyase activity	IEP	Predicted GO
MF	GO:0004089	carbonate dehydratase activity	IEP	Predicted GO
MF	GO:0005216	ion channel activity	IEP	Predicted GO
MF	GO:0005315	inorganic phosphate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0005996	monosaccharide metabolic process	IEP	Predicted GO
BP	GO:0006006	glucose metabolic process	IEP	Predicted GO
BP	GO:0006094	gluconeogenesis	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006813	potassium ion transport	IEP	Predicted GO
BP	GO:0006817	phosphate ion transport	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015267	channel activity	IEP	Predicted GO
MF	GO:0015291	secondary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015298	solute:cation antiporter activity	IEP	Predicted GO
MF	GO:0015299	solute:proton antiporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
BP	GO:0016226	iron-sulfur cluster assembly	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016840	carbon-nitrogen lyase activity	IEP	Predicted GO
MF	GO:0016841	ammonia-lyase activity	IEP	Predicted GO
BP	GO:0019318	hexose metabolic process	IEP	Predicted GO
BP	GO:0019319	hexose biosynthetic process	IEP	Predicted GO
MF	GO:0022803	passive transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022838	substrate-specific channel activity	IEP	Predicted GO
BP	GO:0031163	metallo-sulfur cluster assembly	IEP	Predicted GO
BP	GO:0046364	monosaccharide biosynthetic process	IEP	Predicted GO
MF	GO:0051536	iron-sulfur cluster binding	IEP	Predicted GO
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Predicted GO
MF	GO:0051540	metal cluster binding	IEP	Predicted GO
MF	GO:0071949	FAD binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	1078	1214
IPR011527	ABC1_TM_dom	731	998
IPR011527	ABC1_TM_dom	135	392
IPR003439	ABC_transporter-like	450	583

External Links

No external refs found!

evm.model.tig00020684.9

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation