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  5. evm.model.tig00020780.43

evm.model.tig00020780.43


Description : (at1g74040 : 127.0) Encodes an active Arabidopsis isopropylmalate synthase IPMS2. Involved in leucine biosynthesis. Do not participate in the chain elongation of glucosinolates. Expressed constitutively throughout the plant. Loss of IPMS2 can be compensated by a second isopropylmalate synthase gene IPMS1 (At1g18500).; 2-isopropylmalate synthase 1 (IMS1); FUNCTIONS IN: 2-isopropylmalate synthase activity; INVOLVED IN: leucine biosynthetic process; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Alpha-isopropylmalate/homocitrate synthase, conserved site (InterPro:IPR002034), 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (InterPro:IPR013709), Pyruvate carboxyltransferase (InterPro:IPR000891), Bacterial 2-isopropylmalate synthase (InterPro:IPR005671); BEST Arabidopsis thaliana protein match is: methylthioalkylmalate synthase-like 4 (TAIR:AT1G18500.1); Has 16891 Blast hits to 16883 proteins in 2449 species: Archae - 499; Bacteria - 8886; Metazoa - 193; Fungi - 474; Plants - 279; Viruses - 0; Other Eukaryotes - 6560 (source: NCBI BLink). & (q39891|leu1_soybn : 117.0) Probable 2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase) (Late nodulin 56) (N-56) - Glycine max (Soybean) & (reliability: 254.0) & (original description: no original description)


Gene families : OG_42_0001355 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001355_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00020780.43
Cluster HCCA clusters: Cluster_133

Target Alias Description ECC score Gene Family Method Actions
MA_113962g0010 No alias (at1g74040 : 219.0) Encodes an active Arabidopsis... 0.01 Orthogroups_2024-Update
Seita.8G026900.1 No alias 2-isopropylmalate synthase *(IPMS) & EC_2.3 acyltransferase 0.02 Orthogroups_2024-Update
Sobic.005G030100.1 No alias 2-isopropylmalate synthase *(IPMS) & EC_2.3 acyltransferase 0.02 Orthogroups_2024-Update
Sobic.008G012400.1 No alias 2-isopropylmalate synthase *(IPMS) & EC_2.3 acyltransferase 0.02 Orthogroups_2024-Update
Solyc08g014130 No alias Isopropylmalate synthase (AHRD V3.3 *** K4CJ46_SOLLC) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000295 adenine nucleotide transmembrane transporter activity IEP Predicted GO
BP GO:0001522 pseudouridine synthesis IEP Predicted GO
MF GO:0004019 adenylosuccinate synthase activity IEP Predicted GO
MF GO:0004133 glycogen debranching enzyme activity IEP Predicted GO
MF GO:0004134 4-alpha-glucanotransferase activity IEP Predicted GO
MF GO:0004611 phosphoenolpyruvate carboxykinase activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004619 phosphoglycerate mutase activity IEP Predicted GO
MF GO:0004645 phosphorylase activity IEP Predicted GO
MF GO:0005346 purine ribonucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0005347 ATP transmembrane transporter activity IEP Predicted GO
MF GO:0005471 ATP:ADP antiporter activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006006 glucose metabolic process IEP Predicted GO
BP GO:0006007 glucose catabolic process IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006094 gluconeogenesis IEP Predicted GO
BP GO:0006098 pentose-phosphate shunt IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006862 nucleotide transport IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008184 glycogen phosphorylase activity IEP Predicted GO
MF GO:0008514 organic anion transmembrane transporter activity IEP Predicted GO
MF GO:0008536 Ran GTPase binding IEP Predicted GO
MF GO:0015215 nucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0015216 purine nucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0015217 ADP transmembrane transporter activity IEP Predicted GO
MF GO:0015238 drug transmembrane transporter activity IEP Predicted GO
MF GO:0015297 antiporter activity IEP Predicted GO
MF GO:0015301 anion:anion antiporter activity IEP Predicted GO
MF GO:0015605 organophosphate ester transmembrane transporter activity IEP Predicted GO
BP GO:0015748 organophosphate ester transport IEP Predicted GO
BP GO:0015931 nucleobase-containing compound transport IEP Predicted GO
MF GO:0015932 nucleobase-containing compound transmembrane transporter activity IEP Predicted GO
CC GO:0016021 integral component of membrane IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016757 transferase activity, transferring glycosyl groups IEP Predicted GO
MF GO:0016758 transferase activity, transferring hexosyl groups IEP Predicted GO
MF GO:0016830 carbon-carbon lyase activity IEP Predicted GO
MF GO:0016831 carboxy-lyase activity IEP Predicted GO
MF GO:0016866 intramolecular transferase activity IEP Predicted GO
MF GO:0016868 intramolecular transferase activity, phosphotransferases IEP Predicted GO
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Predicted GO
MF GO:0017016 Ras GTPase binding IEP Predicted GO
BP GO:0019318 hexose metabolic process IEP Predicted GO
BP GO:0019319 hexose biosynthetic process IEP Predicted GO
BP GO:0019320 hexose catabolic process IEP Predicted GO
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
MF GO:0022804 active transmembrane transporter activity IEP Predicted GO
MF GO:0030145 manganese ion binding IEP Predicted GO
CC GO:0031224 intrinsic component of membrane IEP Predicted GO
MF GO:0031267 small GTPase binding IEP Predicted GO
BP GO:0042254 ribosome biogenesis IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
BP GO:0046364 monosaccharide biosynthetic process IEP Predicted GO
BP GO:0046365 monosaccharide catabolic process IEP Predicted GO
MF GO:0050661 NADP binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051156 glucose 6-phosphate metabolic process IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0099516 ion antiporter activity IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
MF GO:1901505 carbohydrate derivative transmembrane transporter activity IEP Predicted GO
InterPro domains Description Start Stop
IPR000891 PYR_CT 42 139
No external refs found!