evm.model.tig00021127.4

Description : (at3g48150 : 429.0) anaphase-promoting complex or cyclosome subunit; anaphase-promoting complex subunit 8 (APC8); FUNCTIONS IN: binding; INVOLVED IN: cell cycle, regulation of mitotic metaphase/anaphase transition; LOCATED IN: anaphase-promoting complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Cdc23 (InterPro:IPR007192), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G16320.1); Has 14789 Blast hits to 8989 proteins in 1164 species: Archae - 889; Bacteria - 6197; Metazoa - 2204; Fungi - 825; Plants - 603; Viruses - 0; Other Eukaryotes - 4071 (source: NCBI BLink). & (reliability: 858.0) & (original description: no original description)

Gene families : OG_42_0004595 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004595_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00021127.4
Cluster	HCCA clusters: Cluster_54

Target	Alias	Description	ECC score	Gene Family Method	Actions
Brara.F01698.1	No alias	component *(APC8) of (APC/C)-dependent ubiquitination...	0.03	Orthogroups_2024-Update
Cre16.g681578	No alias	anaphase-promoting complex subunit 8	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	None	Extended
CC	GO:0000152	nuclear ubiquitin ligase complex	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005680	anaphase-promoting complex	IEA	InterProScan predictions
BP	GO:0007088	regulation of mitotic nuclear division	None	Extended
BP	GO:0007346	regulation of mitotic cell cycle	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0010564	regulation of cell cycle process	None	Extended
BP	GO:0010965	regulation of mitotic sister chromatid separation	None	Extended
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEA	InterProScan predictions
CC	GO:0031461	cullin-RING ubiquitin ligase complex	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033043	regulation of organelle organization	None	Extended
BP	GO:0033044	regulation of chromosome organization	None	Extended
BP	GO:0033045	regulation of sister chromatid segregation	None	Extended
BP	GO:0033047	regulation of mitotic sister chromatid segregation	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044428	nuclear part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051726	regulation of cell cycle	None	Extended
BP	GO:0051783	regulation of nuclear division	None	Extended
BP	GO:0051983	regulation of chromosome segregation	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:1901987	regulation of cell cycle phase transition	None	Extended
BP	GO:1901990	regulation of mitotic cell cycle phase transition	None	Extended
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
BP	GO:1905818	regulation of chromosome separation	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0003896	DNA primase activity	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Predicted GO
MF	GO:0004797	thymidine kinase activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006231	dTMP biosynthetic process	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006310	DNA recombination	IEP	Predicted GO
BP	GO:0006325	chromatin organization	IEP	Predicted GO
BP	GO:0006333	chromatin assembly or disassembly	IEP	Predicted GO
BP	GO:0006401	RNA catabolic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Predicted GO
MF	GO:0019136	deoxynucleoside kinase activity	IEP	Predicted GO
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Predicted GO
MF	GO:0019206	nucleoside kinase activity	IEP	Predicted GO
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Predicted GO
CC	GO:0032299	ribonuclease H2 complex	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0046073	dTMP metabolic process	IEP	Predicted GO
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0050797	thymidylate synthase (FAD) activity	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051052	regulation of DNA metabolic process	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR019734	TPR_repeat	384	407
IPR019734	TPR_repeat	295	326
IPR019734	TPR_repeat	329	358
IPR007192	APC8	61	104
IPR007192	APC8	8	40

External Links

No external refs found!

evm.model.tig00021127.4

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation