Kfl00044_0300 (kfl00044_0300_v1.1)

Aliases : kfl00044_0300_v1.1

Description : (q43058|hem2_phypa : 503.0) Delta-aminolevulinic acid dehydratase, chloroplast precursor (EC 4.2.1.24) (Porphobilinogen synthase) (ALADH) - Physcomitrella patens (Moss) & (at1g69740 : 478.0) Encodes a putative 5-aminolevulinate dehydratase involved in chlorophyll biosynthesis.; HEMB1; FUNCTIONS IN: porphobilinogen synthase activity, catalytic activity, metal ion binding; INVOLVED IN: porphyrin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Tetrapyrrole biosynthesis, porphobilinogen synthase (InterPro:IPR001731); BEST Arabidopsis thaliana protein match is: Aldolase superfamily protein (TAIR:AT1G44318.1); Has 6820 Blast hits to 6820 proteins in 2111 species: Archae - 162; Bacteria - 3714; Metazoa - 160; Fungi - 160; Plants - 86; Viruses - 0; Other Eukaryotes - 2538 (source: NCBI BLink). & (reliability: 956.0) & (original description: no original description)

Gene families : OG_42_0006940 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006940_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00044_0300
Cluster	HCCA clusters: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method
Bradi1g34513	No alias	Aldolase superfamily protein	0.04	Orthogroups_2024-Update
Bradi3g03360	No alias	Aldolase superfamily protein	0.03	Orthogroups_2024-Update
Brara.G02906.1	No alias	porphobilinogen synthase *(HEMB) & EC_4.2 carbon-oxygen lyase	0.01	Orthogroups_2024-Update
Cre02.g091050	No alias	Aldolase superfamily protein	0.05	Orthogroups_2024-Update
Glyma.04G247700	No alias	Aldolase superfamily protein	0.02	Orthogroups_2024-Update
LOC_Os06g49110	No alias	delta-aminolevulinic acid dehydratase, chloroplast...	0.01	Orthogroups_2024-Update
Mp1g22820.1	No alias	porphobilinogen synthase	0.04	Orthogroups_2024-Update
Potri.002G082300	No alias	Aldolase superfamily protein	0.03	Orthogroups_2024-Update
Pp1s219_94V6	No alias	ala dehydratase	0.03	Orthogroups_2024-Update
Pp1s450_21V6	No alias	ala dehydratase	0.02	Orthogroups_2024-Update
Sobic.010G255100.1	No alias	porphobilinogen synthase *(HEMB) & EC_4.2 carbon-oxygen lyase	0.02	Orthogroups_2024-Update
evm.model.tig00001154.8	No alias	(q42836\|hem2_horvu : 356.0) Delta-aminolevulinic acid...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004655	porphobilinogen synthase activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016835	carbon-oxygen lyase activity	None	Extended
MF	GO:0016836	hydro-lyase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	IEA	InterProScan predictions
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	IEA	InterProScan predictions
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0004109	coproporphyrinogen oxidase activity	IEP	Predicted GO
MF	GO:0004560	alpha-L-fucosidase activity	IEP	Predicted GO
MF	GO:0004751	ribose-5-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Predicted GO
MF	GO:0005315	inorganic phosphate transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0006817	phosphate ion transport	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
BP	GO:0009052	pentose-phosphate shunt, non-oxidative branch	IEP	Predicted GO
CC	GO:0009521	photosystem	IEP	Predicted GO
CC	GO:0009522	photosystem I	IEP	Predicted GO
CC	GO:0009523	photosystem II	IEP	Predicted GO
CC	GO:0009538	photosystem I reaction center	IEP	Predicted GO
CC	GO:0009654	photosystem II oxygen evolving complex	IEP	Predicted GO
MF	GO:0015928	fucosidase activity	IEP	Predicted GO
BP	GO:0015979	photosynthesis	IEP	Predicted GO
MF	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Predicted GO
CC	GO:0019898	extrinsic component of membrane	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
CC	GO:0044436	thylakoid part	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051188	cofactor biosynthetic process	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
CC	GO:1990204	oxidoreductase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001731	ALAD	117	433

External Links

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Kfl00044_0300 (kfl00044_0300_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation