Kfl00133_0290 (kfl00133_0290_v1.1,...)


Aliases : kfl00133_0290_v1.1, kfl00133_0290_v1.1

Description : (at3g25530 : 329.0) Encodes gamma-hydroxybutyrate dehydrogenase (AtGHBDH). Contains a NADP-binding domain. GHBDH is proposed to function in oxidative stress tolerance.; glyoxylate reductase 1 (GLYR1); FUNCTIONS IN: 3-hydroxybutyrate dehydrogenase activity, phosphogluconate dehydrogenase (decarboxylating) activity; INVOLVED IN: response to oxidative stress; LOCATED IN: cytosol; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: glyoxylate reductase 2 (TAIR:AT1G17650.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 602.0) & (original description: no original description)


Gene families : OG_42_0002564 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002564_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00133_0290
Cluster HCCA clusters: Cluster_47

Target Alias Description ECC score Gene Family Method Actions
PSME_00047769-RA No alias (at3g25530 : 143.0) Encodes gamma-hydroxybutyrate... 0.02 Orthogroups_2024-Update
Seita.5G207800.1 No alias bifunctional gamma-hydroxybutyrate dehydrogenase and... 0.02 Orthogroups_2024-Update
evm.model.tig00020941.34 No alias (at3g25530 : 209.0) Encodes gamma-hydroxybutyrate... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0050661 NADP binding IEA InterProScan predictions
MF GO:0051287 NAD binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000041 transition metal ion transport IEP Predicted GO
MF GO:0003697 single-stranded DNA binding IEP Predicted GO
MF GO:0004857 enzyme inhibitor activity IEP Predicted GO
MF GO:0004866 endopeptidase inhibitor activity IEP Predicted GO
MF GO:0004867 serine-type endopeptidase inhibitor activity IEP Predicted GO
CC GO:0005741 mitochondrial outer membrane IEP Predicted GO
CC GO:0005743 mitochondrial inner membrane IEP Predicted GO
CC GO:0005750 mitochondrial respiratory chain complex III IEP Predicted GO
CC GO:0005758 mitochondrial intermembrane space IEP Predicted GO
BP GO:0006091 generation of precursor metabolites and energy IEP Predicted GO
BP GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c IEP Predicted GO
BP GO:0006825 copper ion transport IEP Predicted GO
BP GO:0009611 response to wounding IEP Predicted GO
BP GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient IEP Predicted GO
BP GO:0015991 ATP hydrolysis coupled proton transport IEP Predicted GO
MF GO:0016530 metallochaperone activity IEP Predicted GO
MF GO:0016531 copper chaperone activity IEP Predicted GO
CC GO:0019866 organelle inner membrane IEP Predicted GO
CC GO:0019867 outer membrane IEP Predicted GO
BP GO:0022900 electron transport chain IEP Predicted GO
BP GO:0022904 respiratory electron transport chain IEP Predicted GO
MF GO:0030414 peptidase inhibitor activity IEP Predicted GO
CC GO:0031090 organelle membrane IEP Predicted GO
CC GO:0031966 mitochondrial membrane IEP Predicted GO
CC GO:0031968 organelle outer membrane IEP Predicted GO
CC GO:0031970 organelle envelope lumen IEP Predicted GO
CC GO:0031974 membrane-enclosed lumen IEP Predicted GO
CC GO:0033179 proton-transporting V-type ATPase, V0 domain IEP Predicted GO
CC GO:0043233 organelle lumen IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044429 mitochondrial part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0045275 respiratory chain complex III IEP Predicted GO
MF GO:0061134 peptidase regulator activity IEP Predicted GO
MF GO:0061135 endopeptidase regulator activity IEP Predicted GO
CC GO:0070013 intracellular organelle lumen IEP Predicted GO
CC GO:0070069 cytochrome complex IEP Predicted GO
CC GO:0070469 respiratory chain IEP Predicted GO
BP GO:0090662 ATP hydrolysis coupled transmembrane transport IEP Predicted GO
CC GO:0098588 bounding membrane of organelle IEP Predicted GO
CC GO:0098803 respiratory chain complex IEP Predicted GO
CC GO:0098805 whole membrane IEP Predicted GO
BP GO:0099131 ATP hydrolysis coupled ion transmembrane transport IEP Predicted GO
BP GO:0099132 ATP hydrolysis coupled cation transmembrane transport IEP Predicted GO
MF GO:0140104 molecular carrier activity IEP Predicted GO
InterPro domains Description Start Stop
IPR006115 6PGDH_NADP-bd 5 160
IPR029154 NADP-bd 166 286
No external refs found!