Kfl00185_0190 (kfl00185_0190_v1.1)

Aliases : kfl00185_0190_v1.1

Description : (at1g18800 : 251.0) Double nrp1-1 nrp2-1 mutants show arrest of cell cycle progression at G2/M and disordered cellular organization occurred in root tips. Localize in the nucleus and can form homomeric and heteromeric protein complexes with NRP1. Bind histones Histone2A and Histone2B and associate with chromatin in vivo.; NAP1-related protein 2 (NRP2); FUNCTIONS IN: chromatin binding, histone binding, DNA binding; INVOLVED IN: cell proliferation, cell differentiation, nucleosome assembly, lateral root formation; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleosome assembly protein (NAP) (InterPro:IPR002164); BEST Arabidopsis thaliana protein match is: NAP1-related protein 1 (TAIR:AT1G74560.2); Has 4380 Blast hits to 3595 proteins in 373 species: Archae - 7; Bacteria - 141; Metazoa - 1827; Fungi - 714; Plants - 336; Viruses - 93; Other Eukaryotes - 1262 (source: NCBI BLink). & (reliability: 502.0) & (original description: no original description)

Gene families : OG_42_0001945 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001945_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00185_0190
Cluster	HCCA clusters: Cluster_43

Target	Alias	Description	ECC score	Gene Family Method	Actions
Bradi3g46800	No alias	NAP1-related protein 2	0.02	Orthogroups_2024-Update
Mp3g22840.1	No alias	histone chaperone (NRP)	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	InterProScan predictions
BP	GO:0006325	chromatin organization	None	Extended
BP	GO:0006334	nucleosome assembly	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0022607	cellular component assembly	None	Extended
BP	GO:0034622	cellular protein-containing complex assembly	None	Extended
BP	GO:0034728	nucleosome organization	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043933	protein-containing complex subunit organization	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0065003	protein-containing complex assembly	None	Extended
BP	GO:0065004	protein-DNA complex assembly	None	Extended
BP	GO:0071824	protein-DNA complex subunit organization	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000075	cell cycle checkpoint	IEP	Predicted GO
CC	GO:0000228	nuclear chromosome	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
BP	GO:0006013	mannose metabolic process	IEP	Predicted GO
BP	GO:0006338	chromatin remodeling	IEP	Predicted GO
BP	GO:0006471	protein ADP-ribosylation	IEP	Predicted GO
BP	GO:0006771	riboflavin metabolic process	IEP	Predicted GO
BP	GO:0007088	regulation of mitotic nuclear division	IEP	Predicted GO
BP	GO:0007093	mitotic cell cycle checkpoint	IEP	Predicted GO
BP	GO:0007094	mitotic spindle assembly checkpoint	IEP	Predicted GO
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
MF	GO:0008531	riboflavin kinase activity	IEP	Predicted GO
BP	GO:0009231	riboflavin biosynthetic process	IEP	Predicted GO
BP	GO:0010564	regulation of cell cycle process	IEP	Predicted GO
BP	GO:0010639	negative regulation of organelle organization	IEP	Predicted GO
BP	GO:0010948	negative regulation of cell cycle process	IEP	Predicted GO
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Predicted GO
BP	GO:0031577	spindle checkpoint	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Predicted GO
BP	GO:0033046	negative regulation of sister chromatid segregation	IEP	Predicted GO
BP	GO:0033047	regulation of mitotic sister chromatid segregation	IEP	Predicted GO
BP	GO:0033048	negative regulation of mitotic sister chromatid segregation	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0045786	negative regulation of cell cycle	IEP	Predicted GO
BP	GO:0045839	negative regulation of mitotic nuclear division	IEP	Predicted GO
BP	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	IEP	Predicted GO
BP	GO:0045930	negative regulation of mitotic cell cycle	IEP	Predicted GO
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Predicted GO
BP	GO:0050789	regulation of biological process	IEP	Predicted GO
BP	GO:0050794	regulation of cellular process	IEP	Predicted GO
BP	GO:0051129	negative regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051783	regulation of nuclear division	IEP	Predicted GO
BP	GO:0051784	negative regulation of nuclear division	IEP	Predicted GO
BP	GO:0051983	regulation of chromosome segregation	IEP	Predicted GO
BP	GO:0051985	negative regulation of chromosome segregation	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
BP	GO:0071173	spindle assembly checkpoint	IEP	Predicted GO
BP	GO:0071174	mitotic spindle checkpoint	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Predicted GO
BP	GO:1901988	negative regulation of cell cycle phase transition	IEP	Predicted GO
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Predicted GO
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	IEP	Predicted GO
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Predicted GO
BP	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO
BP	GO:1905818	regulation of chromosome separation	IEP	Predicted GO
BP	GO:1905819	negative regulation of chromosome separation	IEP	Predicted GO
BP	GO:2000816	negative regulation of mitotic sister chromatid separation	IEP	Predicted GO
BP	GO:2001251	negative regulation of chromosome organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002164	NAP_family	84	231

External Links

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Kfl00185_0190 (kfl00185_0190_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation