Kfl00194_0180 (kfl00194_0180_v1.1)

Aliases : kfl00194_0180_v1.1

Description : (at3g10690 : 898.0) DNA GYRASE A (GYRA); FUNCTIONS IN: DNA topoisomerase activity, catalytic activity, ATP binding; INVOLVED IN: DNA topological change, DNA metabolic process; LOCATED IN: mitochondrion, chloroplast, nucleoid; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA gyrase, subunit A (InterPro:IPR005743), DNA topoisomerase, type IIA, subunit A/C-terminal (InterPro:IPR002205), DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta (InterPro:IPR013758), DNA topoisomerase, type IIA, subunit A, alpha-helical (InterPro:IPR013757), DNA topoisomerase, type IIA, central (InterPro:IPR013760), DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel (InterPro:IPR006691); BEST Arabidopsis thaliana protein match is: topoisomerase II (TAIR:AT3G23890.1); Has 22353 Blast hits to 21396 proteins in 3265 species: Archae - 84; Bacteria - 12907; Metazoa - 182; Fungi - 204; Plants - 111; Viruses - 99; Other Eukaryotes - 8766 (source: NCBI BLink). & (q7xzf7|gyra_orysa : 843.0) Probable DNA gyrase subunit A, chloroplast/mitochondrial precursor (EC 5.99.1.3) - Oryza sativa (Rice) & (reliability: 1796.0) & (original description: no original description)

Gene families : OG_42_0007912 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007912_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00194_0180
Cluster	HCCA clusters: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
At3g10690	No alias	DNA gyrase subunit A, chloroplastic/mitochondrial...	0.02	Orthogroups_2024-Update
Bradi1g04210	No alias	DNA GYRASE A	0.02	Orthogroups_2024-Update
Brara.C03335.1	No alias	subunit A of DNA gyrase complex	0.03	Orthogroups_2024-Update
Cre04.g221650	No alias	DNA GYRASE A	0.01	Orthogroups_2024-Update
Pp1s122_165V6	No alias	dna a subunit	0.02	Orthogroups_2024-Update
Seita.9G040400.1	No alias	subunit A of DNA gyrase complex	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	InterProScan predictions
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
MF	GO:0061505	DNA topoisomerase II activity	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000213	tRNA-intron endonuclease activity	IEP	Predicted GO
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	IEP	Predicted GO
BP	GO:0001510	RNA methylation	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003968	RNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0004549	tRNA-specific ribonuclease activity	IEP	Predicted GO
MF	GO:0004857	enzyme inhibitor activity	IEP	Predicted GO
MF	GO:0004860	protein kinase inhibitor activity	IEP	Predicted GO
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006644	phospholipid metabolic process	IEP	Predicted GO
BP	GO:0006771	riboflavin metabolic process	IEP	Predicted GO
BP	GO:0007050	cell cycle arrest	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008175	tRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008531	riboflavin kinase activity	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
BP	GO:0008654	phospholipid biosynthetic process	IEP	Predicted GO
MF	GO:0008759	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	IEP	Predicted GO
BP	GO:0009231	riboflavin biosynthetic process	IEP	Predicted GO
BP	GO:0009245	lipid A biosynthetic process	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016426	tRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters	IEP	Predicted GO
MF	GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
MF	GO:0019210	kinase inhibitor activity	IEP	Predicted GO
MF	GO:0019213	deacetylase activity	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
MF	GO:0030291	protein serine/threonine kinase inhibitor activity	IEP	Predicted GO
BP	GO:0030488	tRNA methylation	IEP	Predicted GO
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
CC	GO:0034708	methyltransferase complex	IEP	Predicted GO
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Predicted GO
CC	GO:0043527	tRNA methyltransferase complex	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0045786	negative regulation of cell cycle	IEP	Predicted GO
BP	GO:0046493	lipid A metabolic process	IEP	Predicted GO
BP	GO:0046834	lipid phosphorylation	IEP	Predicted GO
BP	GO:0046854	phosphatidylinositol phosphorylation	IEP	Predicted GO
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Predicted GO
MF	GO:0051011	microtubule minus-end binding	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0070925	organelle assembly	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1901269	lipooligosaccharide metabolic process	IEP	Predicted GO
BP	GO:1901271	lipooligosaccharide biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002205	Topo_IIA_A/C	177	611
IPR006691	GyrA/parC_rep	805	844
IPR006691	GyrA/parC_rep	872	916
IPR006691	GyrA/parC_rep	757	799
IPR006691	GyrA/parC_rep	929	974
IPR006691	GyrA/parC_rep	701	751
IPR006691	GyrA/parC_rep	653	697

External Links

No external refs found!

Kfl00194_0180 (kfl00194_0180_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation