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GO:0003918: DNA topoisomerase type II (ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192]


There are 4507 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_129 Solanum lycopersicum 1.27 % 0.009321 0.047113
Cluster_71 Solanum pennellii 2.0 % 2.9e-05 0.000286
Cluster_39 Picea abies 3.28 % 1.6e-05 0.00019
Cluster_224 Pseudotsuga menziesii 1.96 % 0.007087 0.043257
Cluster_71 Brachypodium distachyon 2.13 % 0.000111 0.000629
Cluster_69 Glycine max 1.09 % 0.00025 0.001353
Cluster_524 Glycine max 2.22 % 0.005943 0.028423
Cluster_509 Glycine max 2.0 % 0.006601 0.044701
Cluster_133 Cyanophora paradoxa 3.77 % 9.4e-05 0.00325
Cluster_210 Zea mays 1.67 % 0.005658 0.043117
cluster_0129 Oryza sativa 0.85 % 0.000107 0.020163
Cluster_297 Hordeum vulgare 1.85 % 0.006777 0.031745
Cluster_207 Hordeum vulgare 2.04 % 0.006151 0.045108
Cluster_61 Hordeum vulgare 1.09 % 0.011524 0.045062
Sequences (4507) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms