Kfl00249_0180 (kfl00249_0180_v1.1,...)

Aliases : kfl00249_0180_v1.1, kfl00249_0180_v1.1

Description : (at2g06510 : 511.0) Encodes a homolog of Replication Protein A that is involved in meiosis I in pollen mother cells. rpa1a mutants have a reduced number of class I crossovers. The protein is located in chromatin-associated foci in early leptotene and can be detected in these foci until late pachytene of meiosis I.; replication protein A 1A (RPA1A); FUNCTIONS IN: DNA binding, nucleic acid binding; INVOLVED IN: in 6 processes; LOCATED IN: nuclear chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Replication factor-a protein 1 Rpa1 (InterPro:IPR004591), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Replication factor A, C-terminal (InterPro:IPR013955), Replication factor-A protein 1, N-terminal (InterPro:IPR007199); BEST Arabidopsis thaliana protein match is: Replication factor-A protein 1-related (TAIR:AT4G19130.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1022.0) & (original description: no original description)

Gene families : OG_42_0002224 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002224_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00249_0180
Cluster	HCCA clusters: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method
At5g45400	No alias	Replication protein A 70 kDa DNA-binding subunit C...	0.02	Orthogroups_2024-Update
Cre17.g718850	No alias	replication protein A 1A	0.02	Orthogroups_2024-Update
evm.model.tig00000823.19	No alias	(at2g06510 : 172.0) Encodes a homolog of Replication...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	InterProScan predictions
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0003690	double-stranded DNA binding	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0003883	CTP synthase activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006098	pentose-phosphate shunt	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006298	mismatch repair	IEP	Predicted GO
BP	GO:0006739	NADP metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007010	cytoskeleton organization	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0042802	identical protein binding	IEP	Predicted GO
MF	GO:0042803	protein homodimerization activity	IEP	Predicted GO
MF	GO:0043015	gamma-tubulin binding	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR031657	REPA_OB_2	380	484
IPR013955	Rep_factor-A_C	539	692
IPR007199	Rep_factor-A_N	4	100
IPR004365	NA-bd_OB_tRNA	270	353

External Links

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Kfl00249_0180 (kfl00249_0180_v1.1,...)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation