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  5. Kfl00266_0120

Kfl00266_0120 (kfl00266_0120_v1.1)


Aliases : kfl00266_0120_v1.1

Description : (at3g24495 : 377.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts.; MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink). & (q9xgc9|msh2_maize : 157.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 754.0) & (original description: no original description)


Gene families : OG_42_0001047 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001047_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00266_0120
Cluster HCCA clusters: Cluster_18

Target Alias Description ECC score Gene Family Method Actions
Brara.C02828.1 No alias component *(MSH6) of MSH2-x mismatch repair heterodimers 0.02 Orthogroups_2024-Update
Cre05.g235750 No alias MUTS homolog 6 0.03 Orthogroups_2024-Update
GRMZM2G110212 No alias MUTS homolog 7 0.02 Orthogroups_2024-Update
Glyma.09G189100 No alias MUTS homolog 7 0.02 Orthogroups_2024-Update
PSME_00045960-RA No alias (at3g24495 : 245.0) encodes a DNA mismatch repair... 0.03 Orthogroups_2024-Update
Seita.5G128200.1 No alias component *(MSH7) of MSH2-x mismatch repair heterodimers 0.02 Orthogroups_2024-Update
Sobic.003G041700.1 No alias component *(MSH7) of MSH2-x mismatch repair heterodimers 0.02 Orthogroups_2024-Update
Solyc01g079520 No alias DNA mismatch repair protein (AHRD V3.3 *** Q6DQL6_PETHY) 0.05 Orthogroups_2024-Update
Sopen01g031290 No alias MutS domain V 0.02 Orthogroups_2024-Update
evm.model.tig00000489.16 No alias (at4g02070 : 188.0) encodes a DNA mismatch repair... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA InterProScan predictions
BP GO:0006298 mismatch repair IEA InterProScan predictions
MF GO:0030983 mismatched DNA binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000774 adenyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0003883 CTP synthase activity IEP Predicted GO
MF GO:0004576 oligosaccharyl transferase activity IEP Predicted GO
MF GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006098 pentose-phosphate shunt IEP Predicted GO
BP GO:0006220 pyrimidine nucleotide metabolic process IEP Predicted GO
BP GO:0006221 pyrimidine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
CC GO:0008250 oligosaccharyltransferase complex IEP Predicted GO
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
CC GO:0009507 chloroplast IEP Predicted GO
CC GO:0009536 plastid IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016877 ligase activity, forming carbon-sulfur bonds IEP Predicted GO
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Predicted GO
CC GO:0019867 outer membrane IEP Predicted GO
MF GO:0042802 identical protein binding IEP Predicted GO
MF GO:0042803 protein homodimerization activity IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
MF GO:0046422 violaxanthin de-epoxidase activity IEP Predicted GO
MF GO:0051087 chaperone binding IEP Predicted GO
BP GO:0051156 glucose 6-phosphate metabolic process IEP Predicted GO
MF GO:0060590 ATPase regulator activity IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR007695 DNA_mismatch_repair_MutS-lik_N 216 327
IPR000432 DNA_mismatch_repair_MutS_C 960 1184
IPR007860 DNA_mmatch_repair_MutS_con_dom 357 404
IPR007696 DNA_mismatch_repair_MutS_core 555 811
No external refs found!